Cellosaurus MEB5 (CVCL_5221)
| Cell line name | MEB5 |
|---|---|
| Synonyms | MEB 5; MEB-5 |
| Accession | CVCL_5221 |
| Resource Identification Initiative | To cite this cell line use: MEB5 (RRID:CVCL_5221) |
| Comments | Characteristics: EGF dependent. When deprived of EGF, about 50% of the cells die due to apoptosis within 24h. The remaining cells differentiated into neurons, astrncytes, or oligndendrocytes within 2 weeks. Doubling time: ~20 hours (PubMed=9719419). Genetic integration: Method=Transduction; Gene=UniProtKB; P03129; Human papillomavirus type 16 protein E7. Genetic integration: Method=Transduction; Gene=UniProtKB; P00552; Transposon Tn5 neo. Transformant: NCBI_TaxID; 333760; Human papillomavirus type 16 (HPV16). Derived from site: In situ; Embryonic brain, forebrain; UBERON=UBERON_0006240. |
| Species of origin | Mus musculus (Mouse)
(NCBI Taxonomy: 10090)
Breed/subspecies: C3H/He. |
| Sex of cell | Sex unspecified |
| Age at sampling | 14-15FD |
| Category | Transformed cell line |
| Web pages | http://www.cells-talk.com/index.php/page/copelibrary?key=MEB5 |
| Publications | PubMed=9719419; DOI=10.1007/s11626-998-0119-5 |
| Cross-references | |
| Cell line collections (Providers) | JCRB; IFO50472
JCRB; JCRB0145 |
| Chemistry resources | ChEMBL-Cells; CHEMBL4295451
ChEMBL-Targets; CHEMBL4296469 PubChem_Cell_line; CVCL_5221 |
| Encyclopedic resources | Wikidata; Q54904993 |
| Entry history | |
| Entry creation | 04-Apr-2012 |
| Last entry update | 10-Sep-2024 |
| Version number | 19 |