ID   MEB5
AC   CVCL_5221
SY   MEB 5; MEB-5
DR   ChEMBL-Cells; CHEMBL4295451
DR   ChEMBL-Targets; CHEMBL4296469
DR   JCRB; IFO50472
DR   JCRB; JCRB0145
DR   PubChem_Cell_line; CVCL_5221
DR   Wikidata; Q54904993
RX   PubMed=9719419;
WW   Info; COPE; -; http://www.cells-talk.com/index.php/page/copelibrary?key=MEB5
CC   Characteristics: EGF dependent. When deprived of EGF, about 50% of the cells die due to apoptosis within 24h. The remaining cells differentiated into neurons, astrncytes, or oligndendrocytes within 2 weeks.
CC   Doubling time: ~20 hours (PubMed=9719419).
CC   Genetic integration: Method=Transduction; Gene=UniProtKB; P03129; Human papillomavirus type 16 protein E7.
CC   Genetic integration: Method=Transduction; Gene=UniProtKB; P00552; Transposon Tn5 neo.
CC   Transformant: NCBI_TaxID; 333760; Human papillomavirus type 16 (HPV16).
CC   Derived from site: In situ; Embryonic brain, forebrain; UBERON=UBERON_0006240.
CC   Breed/subspecies: C3H/He.
OX   NCBI_TaxID=10090; ! Mus musculus (Mouse)
SX   Sex unspecified
AG   14-15FD
CA   Transformed cell line
DT   Created: 04-04-12; Last updated: 10-04-25; Version: 20
//
RX   PubMed=9719419; DOI=10.1007/s11626-998-0119-5;
RA   Nakagaito Y., Satoh M., Kuno H., Iwama T., Takeuchi M., Hakura A.,
RA   Yoshida T.;
RT   "Establishment of an epidermal growth factor-dependent, multipotent
RT   neural precursor cell line.";
RL   In Vitro Cell. Dev. Biol. Anim. 34:585-592(1998).
//