• Gene deletion; HGNC; HGNC:6515; LATS2; Zygosity=Homozygous (PubMed=21245096).
  

PubMed=19380521; DOI=10.1093/carcin/bgp097
Koji Kawaguchi, Hideki Murakami, Tetsuo Taniguchi, Makiko Fujii, Shigehisa Kawata, Takayuki Fukui, Yutaka Kondo, Hirotaka Osada, Noriyasu Usami, Kohei Yokoi, Yuichi Ueda ...Show all 16 authors... , Yasushi Yatabe, Masafumi Ito, Yoshitsugu Horio, Toyoaki Hida, Yoshitaka Sekido; Show fewer authors
Combined inhibition of MET and EGFR suppresses proliferation of malignant mesothelioma cells.
Carcinogenesis 30:1097-1105(2009)

PubMed=21245096; DOI=10.1158/0008-5472.CAN-10-2164
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LATS2 is a tumor suppressor gene of malignant mesothelioma.
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Tetsuya Mizuno, Hideki Murakami, Makiko Fujii, Futoshi Ishiguro, Issei Tanaka, Yutaka Kondo, Shinya Akatsuka, Shinya Toyokuni, Kohei Yokoi, Hirotaka Osada, Yoshitaka Sekido;
YAP induces malignant mesothelioma cell proliferation by upregulating transcription of cell cycle-promoting genes.
Oncogene 31:5117-5122(2012)

PubMed=26011428; DOI=10.1111/cas.12698; PMCID=PMC4556387
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Functional differences between wild-type and mutant-type BRCA1-associated protein 1 tumor suppressor against malignant mesothelioma cells.
Cancer Sci. 106:990-999(2015)

PubMed=28553954; DOI=10.1038/onc.2017.147
T. Kato, Tatsuhiro Sato, Kohei Yokoi, Yoshitaka Sekido;
E-cadherin expression is correlated with focal adhesion kinase inhibitor resistance in merlin-negative malignant mesothelioma cells.
Oncogene 36:5522-5531(2017)