ID   Y-MESO-27
AC   CVCL_5184
DR   cancercelllines; CVCL_5184
DR   Cosmic; 2759222
DR   GEO; GSM552533
DR   GEO; GSM850292
DR   Progenetix; CVCL_5184
DR   RCB; RCB5672
DR   Wikidata; Q54995145
RX   PubMed=19380521;
RX   PubMed=21245096;
RX   PubMed=22286761;
RX   PubMed=26011428;
RX   PubMed=28553954;
CC   Population: Japanese.
CC   Sequence variation: Gene deletion; HGNC; HGNC:6515; LATS2; Zygosity=Homozygous (PubMed=21245096).
CC   Omics: Transcriptomics; Microarray.
CC   Omics: Variations; Array-based CGH.
ST   Source(s): RCB=RCB5672
ST   Amelogenin: X
ST   CSF1PO: 10,12
ST   D13S317: 8
ST   D16S539: 9
ST   D5S818: 11,12
ST   D7S820: 11
ST   TH01: 9
ST   TPOX: 9,10
ST   vWA: 19,20
DI   NCIt; C45662; Pleural epithelioid mesothelioma
DI   ORDO; Orphanet_50251; Pleural mesothelioma
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
SX   Male
AG   57Y
CA   Cancer cell line
DT   Created: 04-04-12; Last updated: 10-04-25; Version: 19
//
RX   PubMed=22286761; DOI=10.1038/onc.2012.5;
RA   Mizuno, Tetsuya
RA   Murakami, Hideki
RA   Fujii, Makiko
RA   Ishiguro, Futoshi
RA   Tanaka, Issei
RA   Kondo, Yutaka
RA   Akatsuka, Shinya
RA   Toyokuni, Shinya
RA   Yokoi, Kohei
RA   Osada, Hirotaka
RA   Sekido, Yoshitaka
RT   "YAP induces malignant mesothelioma cell proliferation by upregulating
RT   transcription of cell cycle-promoting genes.";
RL   Oncogene 31:5117-5122(2012).
//
RX   PubMed=28553954; DOI=10.1038/onc.2017.147;
RA   Kato, Taketo
RA   Sato, Tatsuhiro
RA   Yokoi, Kohei
RA   Sekido, Yoshitaka
RT   "E-cadherin expression is correlated with focal adhesion kinase
RT   inhibitor resistance in merlin-negative malignant mesothelioma
RT   cells.";
RL   Oncogene 36:5522-5531(2017).
//
RX   PubMed=19380521; DOI=10.1093/carcin/bgp097;
RA   Kawaguchi, Koji
RA   Murakami, Hideki
RA   Taniguchi, Tetsuo
RA   Fujii, Makiko
RA   Kawata, Shigehisa
RA   Fukui, Takayuki
RA   Kondo, Yutaka
RA   Osada, Hirotaka
RA   Usami, Noriyasu
RA   Yokoi, Kohei
RA   Ueda, Yuichi
RA   Yatabe, Yasushi
RA   Ito, Masafumi
RA   Horio, Yoshitsugu
RA   Hida, Toyoaki
RA   Sekido, Yoshitaka
RT   "Combined inhibition of MET and EGFR suppresses proliferation of
RT   malignant mesothelioma cells.";
RL   Carcinogenesis 30:1097-1105(2009).
//
RX   PubMed=26011428; DOI=10.1111/cas.12698; PMCID=PMC4556387;
RA   Hakiri, Shuhei
RA   Osada, Hirotaka
RA   Ishiguro, Futoshi
RA   Murakami, Hideki
RA   Murakami-Tonami, Yuko
RA   Yokoi, Kohei
RA   Sekido, Yoshitaka
RT   "Functional differences between wild-type and mutant-type
RT   BRCA1-associated protein 1 tumor suppressor against malignant
RT   mesothelioma cells.";
RL   Cancer Sci. 106:990-999(2015).
//
RX   PubMed=21245096; DOI=10.1158/0008-5472.CAN-10-2164;
RA   Murakami, Hideki
RA   Mizuno, Tetsuya
RA   Taniguchi, Tetsuo
RA   Fujii, Makiko
RA   Ishiguro, Futoshi
RA   Fukui, Takayuki
RA   Akatsuka, Shinya
RA   Horio, Yoshitsugu
RA   Hida, Toyoaki
RA   Kondo, Yutaka
RA   Toyokuni, Shinya
RA   Osada, Hirotaka
RA   Sekido, Yoshitaka
RT   "LATS2 is a tumor suppressor gene of malignant mesothelioma.";
RL   Cancer Res. 71:873-883(2011).
//