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Cellosaurus SNU-70 (CVCL_5084)

[Text version]
Cell line name SNU-70
Synonyms SNU70
Accession CVCL_5084
Resource Identification Initiative To cite this cell line use: SNU-70 (RRID:CVCL_5084)
Comments Part of: Seoul National University (SNU) cell line collection.
Population: Korean.
Doubling time: 118 hours (PubMed=20176655).
Microsatellite instability: Stable (MSS) (PubMed=20176655).
Omics: Transcriptomics; Microarray.
Derived from site: In situ; Rectum; UBERON=UBERON_0001052.
Sequence variations
  • Mutation; HGNC; HGNC:583; APC; Simple; p.Gln1294Ter (c.3880C>T); ClinVar=VCV000469942; Zygosity=Unspecified (PubMed=20176655).
  • Mutation; HGNC; HGNC:11998; TP53; Simple; p.Arg282fs (c.845delG); Zygosity=Homozygous (PubMed=20176655).
Disease Rectal adenocarcinoma (NCIt: C9383)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell Male
Age at sampling 61Y
Category Cancer cell line
STR profile Source(s): KCLB=00070; PubMed=20176655

Markers:
AmelogeninX,Y
CSF1PO10,12
D2S133818,19
D3S135815,16
D5S81810,11
D7S8208,11
D8S117912,14
D13S3178,12
D16S53911
D18S5113
D19S43314
D21S1131,32.2
FGA21
TH017,9
TPOX8,9
vWA16,19

Run an STR similarity search on this cell line
Publications

PubMed=20176655; DOI=10.1093/carcin/bgq043
Ja-Lok Ku, Young-Kyoung Shin, Duck-Woo Kim, Kyung-Hee Kim, Jin-Sung Choi, Sung-Hye Hong, You-Kyung Jeon, Sung-Hee Kim, Hong-Sun Kim, Jae-Hyun Park, Il-Jin Kim, Jae-Gahb Park;
Establishment and characterization of 13 human colorectal carcinoma cell lines: mutations of genes and expressions of drug-sensitivity genes and cancer stem cell markers.
Carcinogenesis 31:1003-1009(2010)

PubMed=25926053; DOI=10.1038/ncomms8002
Enzo Medico, Mariangela Russo, Gabriele Picco, Carlotta Cancelliere, Emanuele Valtorta, Giorgio Corti, Michela Buscarino, Claudio Isella, Simona Lamba, Barbara Martinoglio, Silvio Veronese ...Show all 19 authors... , Salvatore Siena, Andrea Sartore-Bianchi, Marco Beccuti, Marcella Mottolese, Michael Linnebacher, Francesca Cordero, Federica Di Nicolantonio, Alberto Bardelli; Show fewer authors
The molecular landscape of colorectal cancer cell lines unveils clinically actionable kinase targets.
Nat. Commun. 6:7002.1-7002.10(2015)

Cross-references
Cell line collections (Providers) KCLB; 00070
Cell line databases/resources cancercelllines; CVCL_5084
ColonAtlas; SNU70
Encyclopedic resources Wikidata; Q54955252
Gene expression databases GEO; GSM1448210
Polymorphism and mutation databases Cosmic; 1322282
IARC_TP53; 28468
Entry history
Entry creation04-Apr-2012
Last entry update10-Apr-2025
Version number23