ID   SNU-70
AC   CVCL_5084
SY   SNU70
DR   cancercelllines; CVCL_5084
DR   ColonAtlas; SNU70
DR   Cosmic; 1322282
DR   GEO; GSM1448210
DR   IARC_TP53; 28468
DR   KCLB; 00070
DR   Wikidata; Q54955252
RX   PubMed=20176655;
RX   PubMed=25926053;
CC   Part of: Seoul National University (SNU) cell line collection.
CC   Population: Korean.
CC   Doubling time: 118 hours (PubMed=20176655).
CC   Microsatellite instability: Stable (MSS) (PubMed=20176655).
CC   Sequence variation: Mutation; HGNC; 583; APC; Simple; p.Gln1294Ter (c.3880C>T); ClinVar=VCV000469942; Zygosity=Unspecified (PubMed=20176655).
CC   Sequence variation: Mutation; HGNC; 11998; TP53; Simple; p.Arg282fs (c.845delG); Zygosity=Homozygous (PubMed=20176655).
CC   Omics: Transcriptome analysis by microarray.
CC   Derived from site: In situ; Rectum; UBERON=UBERON_0001052.
ST   Source(s): KCLB=00070; PubMed=20176655
ST   Amelogenin: X,Y
ST   CSF1PO: 10,12
ST   D13S317: 8,12
ST   D16S539: 11
ST   D18S51: 13
ST   D19S433: 14
ST   D21S11: 31,32.2
ST   D2S1338: 18,19
ST   D3S1358: 15,16
ST   D5S818: 10,11
ST   D7S820: 8,11
ST   D8S1179: 12,14
ST   FGA: 21
ST   TH01: 7,9
ST   TPOX: 8,9
ST   vWA: 16,19
DI   NCIt; C9383; Rectal adenocarcinoma
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
SX   Male
AG   61Y
CA   Cancer cell line
DT   Created: 04-04-12; Last updated: 02-05-24; Version: 21
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RX   PubMed=20176655; DOI=10.1093/carcin/bgq043;
RA   Ku J.-L., Shin Y.-K., Kim D.-W., Kim K.-H., Choi J.-S., Hong S.-H.,
RA   Jeon Y.-K., Kim S.-H., Kim H.-S., Park J.-H., Kim I.-J., Park J.-G.;
RT   "Establishment and characterization of 13 human colorectal carcinoma
RT   cell lines: mutations of genes and expressions of drug-sensitivity
RT   genes and cancer stem cell markers.";
RL   Carcinogenesis 31:1003-1009(2010).
//
RX   PubMed=25926053; DOI=10.1038/ncomms8002;
RA   Medico E., Russo M., Picco G., Cancelliere C., Valtorta E., Corti G.,
RA   Buscarino M., Isella C., Lamba S., Martinoglio B., Veronese S.,
RA   Siena S., Sartore-Bianchi A., Beccuti M., Mottolese M.,
RA   Linnebacher M., Cordero F., Di Nicolantonio F., Bardelli A.;
RT   "The molecular landscape of colorectal cancer cell lines unveils
RT   clinically actionable kinase targets.";
RL   Nat. Commun. 6:7002.1-7002.10(2015).
//