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Cellosaurus UKF-Rhb-1 (CVCL_4Z17)

[Text version]
Cell line name UKF-Rhb-1
Accession CVCL_4Z17
Resource Identification Initiative To cite this cell line use: UKF-Rhb-1 (RRID:CVCL_4Z17)
Comments Derived from site: Metastatic; Bone marrow; UBERON=UBERON_0002371.
Disease Alveolar rhabdomyosarcoma (NCIt: C3749)
Alveolar rhabdomyosarcoma (ORDO: Orphanet_99756)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Children:
CVCL_RQ48 (UKF-Rhb-1rCDDP1000)CVCL_RQ49 (UKF-Rhb-1rDOCE10)CVCL_RT27 (UKF-Rhb-1rDOCE20)
CVCL_RQ56 (UKF-Rhb-1rDOX10)CVCL_RT28 (UKF-Rhb-1rDOX20)CVCL_RQ57 (UKF-Rhb-1rGEMCI10)
CVCL_RQ58 (UKF-Rhb-1rIRINO200)CVCL_RQ59 (UKF-Rhb-1rMEL400)CVCL_RS17 (UKF-Rhb-1rNutlin10muM)
CVCL_RQ60 (UKF-Rhb-1rOXALI1000)CVCL_4Z18 (UKF-Rhb-1rVCR10)
Category Cancer cell line
Publications

PubMed=19147553; DOI=10.1158/0008-5472.CAN-08-1856
Martin Michaelis, Florian Rothweiler, Denise Klassert, Andreas von Deimling, Kristoffer Weber, Boris Fehse, Bernd Kammerer, Hans-Wilhelm Doerr, Jindrich Cinatl Jr.;
Reversal of P-glycoprotein-mediated multidrug resistance by the murine double minute 2 antagonist nutlin-3.
Cancer Res. 69:416-421(2009)

PubMed=22170099; DOI=10.1038/cddis.2011.129; PMCID=PMC3252738
Martin Michaelis, Florian Rothweiler, Susanne Barth, Jaroslaw Cinatl, Marijke van Rikxoort, Nadine Loschmann, Yvonne Voges, Rainer Breitling, Andreas von Deimling, Franz Rodel, Kristoffer Weber ...Show all 17 authors... , Boris Fehse, Elisabeth Mack, Thorsten Stiewe, Hans-Wilhelm Doerr, Daniel Speidel, Jindrich Cinatl Jr.; Show fewer authors
Adaptation of cancer cells from different entities to the MDM2 inhibitor nutlin-3 results in the emergence of p53-mutated multi-drug-resistant cancer cells.
Cell Death Dis. 2:e243.1-e243.8(2011)

PubMed=23665679; DOI=10.1038/onc.2013.129
Elizabeth I. Sokolowski, Claire B. Turina, Ken Kikuchi, David M. Langenau, Charles Keller;
Proof-of-concept rare cancers in drug development: the case for rhabdomyosarcoma.
Oncogene 33:1877-1889(2014)

Cross-references
Encyclopedic resources Wikidata; Q54990406
Entry history
Entry creation14-Dec-2015
Last entry update29-Jun-2023
Version number8