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Cellosaurus WRLS1 (CVCL_4W86)

[Text version]
Cell line name WRLS1
Accession CVCL_4W86
Resource Identification Initiative To cite this cell line use: WRLS1 (RRID:CVCL_4W86)
Comments Problematic cell line: Contaminated. Parent cell line (WRL-68) has been shown to be a HeLa derivative.
Population: African American.
Selected for resistance to: ChEBI; CHEBI:50924; Sorafenib (Nexavar).
Transformant: NCBI_TaxID; 333761; Human papillomavirus type 18 (HPV18).
Derived from site: In situ; Uterus, cervix; UBERON=UBERON_0000002.
Disease Human papillomavirus-related cervical adenocarcinoma (NCIt: C27677)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_0581 (WRL 68)
Sex of cell Female
Age at sampling 30Y6M
Category Cancer cell line

PubMed=23111106; DOI=10.1016/j.canlet.2012.10.021
van Malenstein H., Dekervel J., Verslype C., Van Cutsem E., Windmolders P., Nevens F., van Pelt J.F.
Long-term exposure to sorafenib of liver cancer cells induces resistance with epithelial-to-mesenchymal transition, increased invasion and risk of rebound growth.
Cancer Lett. 329:74-83(2013)

Encyclopedic resources Wikidata; Q54994416
Entry history
Entry creation14-Dec-2015
Last entry update05-Oct-2023
Version number11