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Cellosaurus NP-8 (CVCL_4W66)

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Cell line name NP-8
Synonyms NP 8; NP8; Case 1
Accession CVCL_4W66
Resource Identification Initiative To cite this cell line use: NP-8 (RRID:CVCL_4W66)
Comments Part of: Cancer Dependency Map project (DepMap) (includes Cancer Cell Line Encyclopedia - CCLE).
Population: Japanese.
Omics: Genomics; Whole exome sequencing.
Derived from site: In situ; Brain, left temporal lobe; UBERON=UBERON_0002808.
Sequence variations
  • Mutation; HGNC; HGNC:1787; CDKN2A; Simple; p.His83Tyr (c.247C>T) (p.Ala97Val, c.290C>T); ClinVar=VCV000376307; Zygosity=Unspecified (PubMed=8878451).
Disease Glioblastoma (NCIt: C3058)
Glioblastoma (ORDO: Orphanet_360)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell Female
Age at sampling 38Y
Category Cancer cell line
STR profile Source(s): DepMap=ACH-001611; JCRB=JCRB1608

Markers:
AmelogeninX
CSF1PO10
D3S135815,17
D5S81810,12
D7S82011,12
D8S117913
D13S3178,11
D16S53911
D18S5113
D21S1128,29
FGA22,23
Penta D11,12
Penta E12,18
TH019
TPOX8,9
vWA18

Run an STR similarity search on this cell line
Publications

PubMed=8878451; DOI=10.1111/j.1349-7006.1996.tb02118.x; PMCID=PMC5921198
Shu-Jing Zhang, Sumio Endo, Hisashi Koga, Tomio Ichikawa, Xue-Lian Feng, Kiyoshi Onda, Kazuo Washiyama, Toshiro Kumanishi;
A comparative study of glioma cell lines for p16, p15, p53 and p21 gene alterations.
Jpn. J. Cancer Res. 87:900-907(1996)

PubMed=10551321; DOI=10.1111/j.1349-7006.1999.tb00838.x; PMCID=PMC5926156
Shu-Jing Zhang, Sumio Endo, Tomio Ichikawa, Jun-ichi Yoshimura, Kiyoshi Onda, Ryuichi Tanaka, Kazuo Washiyama, Toshiro Kumanishi;
Rare-type mutations of MMAC1 tumor suppressor gene in human glioma cell lines and their tumors of origin.
Jpn. J. Cancer Res. 90:934-941(1999)

PubMed=18415661; DOI=10.1007/s10014-007-0226-0
Yoshiyuki Tanaka, Shu-Jing Zhang, Hiroshi Terasaki, Hisashi Koga, Sumio Endo, Hiroshi Usui, Kazuo Washiyama, Toshiro Kumanishi, Yuji Uematsu, Toru Itakura;
Frequent and variable abnormalities in p14 tumor suppressor gene in glioma cell lines.
Brain Tumor Pathol. 25:9-17(2008)

Cross-references
Cell line collections (Providers) JCRB; JCRB1608
Cell line databases/resources cancercelllines; CVCL_4W66
Cell_Model_Passport; SIDM01381
DepMap; ACH-001611
Encyclopedic resources Wikidata; Q54930959
Entry history
Entry creation14-Dec-2015
Last entry update10-Apr-2025
Version number16