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Cellosaurus NP-8 (CVCL_4W66)

[Text version]
Cell line name NP-8
Synonyms NP 8; NP8; Case 1
Accession CVCL_4W66
Resource Identification Initiative To cite this cell line use: NP-8 (RRID:CVCL_4W66)
Comments Part of: Cancer Dependency Map project (DepMap) (includes Cancer Cell Line Encyclopedia - CCLE).
Population: Japanese.
Omics: Deep exome analysis.
Derived from site: In situ; Brain, left temporal lobe; UBERON=UBERON_0002808.
Sequence variations
  • Mutation; HGNC; 1787; CDKN2A; Simple; p.His83Tyr (c.247C>T) (p.Ala97Val, c.290C>T); ClinVar=VCV000376307; Zygosity=Unspecified (PubMed=8878451).
Disease Glioblastoma (NCIt: C3058)
Glioblastoma (ORDO: Orphanet_360)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell Female
Age at sampling 38Y
Category Cancer cell line
STR profile Source(s): DepMap=ACH-001611; JCRB=JCRB1608

Markers:
AmelogeninX
CSF1PO10
D3S135815,17
D5S81810,12
D7S82011,12
D8S117913
D13S3178,11
D16S53911
D18S5113
D21S1128,29
FGA22,23
Penta D11,12
Penta E12,18
TH019
TPOX8,9
vWA18

Run an STR similarity search on this cell line
Publications

PubMed=8878451; DOI=10.1111/j.1349-7006.1996.tb02118.x; PMCID=PMC5921198
Zhang S., Endo S., Koga H., Ichikawa T., Feng X., Onda K., Washiyama K., Kumanishi T.
A comparative study of glioma cell lines for p16, p15, p53 and p21 gene alterations.
Jpn. J. Cancer Res. 87:900-907(1996)

PubMed=10551321; DOI=10.1111/j.1349-7006.1999.tb00838.x; PMCID=PMC5926156
Zhang S.-J., Endo S., Ichikawa T., Yoshimura J., Onda K., Tanaka R., Washiyama K., Kumanishi T.
Rare-type mutations of MMAC1 tumor suppressor gene in human glioma cell lines and their tumors of origin.
Jpn. J. Cancer Res. 90:934-941(1999)

PubMed=18415661; DOI=10.1007/s10014-007-0226-0
Tanaka Y., Zhang S.-J., Terasaki H., Koga H., Endo S., Usui H., Washiyama K., Kumanishi T., Uematsu Y., Itakura T.
Frequent and variable abnormalities in p14 tumor suppressor gene in glioma cell lines.
Brain Tumor Pathol. 25:9-17(2008)

Cross-references
Cell line collections (Providers) JCRB; JCRB1608
Cell line databases/resources cancercelllines; CVCL_4W66
Cell_Model_Passport; SIDM01381
DepMap; ACH-001611
Encyclopedic resources Wikidata; Q54930959
Entry history
Entry creation14-Dec-2015
Last entry update02-May-2024
Version number14