ID   NP-8
AC   CVCL_4W66
SY   NP 8; NP8; Case 1
DR   cancercelllines; CVCL_4W66
DR   Cell_Model_Passport; SIDM01381
DR   DepMap; ACH-001611
DR   JCRB; JCRB1608
DR   Wikidata; Q54930959
RX   PubMed=8878451;
RX   PubMed=10551321;
RX   PubMed=18415661;
CC   Part of: Cancer Dependency Map project (DepMap) (includes Cancer Cell Line Encyclopedia - CCLE).
CC   Population: Japanese.
CC   Sequence variation: Mutation; HGNC; 1787; CDKN2A; Simple; p.His83Tyr (c.247C>T) (p.Ala97Val, c.290C>T); ClinVar=VCV000376307; Zygosity=Unspecified (PubMed=8878451).
CC   Omics: Deep exome analysis.
CC   Derived from site: In situ; Brain, left temporal lobe; UBERON=UBERON_0002808.
ST   Source(s): DepMap=ACH-001611; JCRB=JCRB1608
ST   Amelogenin: X
ST   CSF1PO: 10
ST   D13S317: 8,11
ST   D16S539: 11
ST   D18S51: 13
ST   D21S11: 28,29
ST   D3S1358: 15,17
ST   D5S818: 10,12
ST   D7S820: 11,12
ST   D8S1179: 13
ST   FGA: 22,23
ST   Penta D: 11,12
ST   Penta E: 12,18
ST   TH01: 9
ST   TPOX: 8,9
ST   vWA: 18
DI   NCIt; C3058; Glioblastoma
DI   ORDO; Orphanet_360; Glioblastoma
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
SX   Female
AG   38Y
CA   Cancer cell line
DT   Created: 14-12-15; Last updated: 02-05-24; Version: 14
//
RX   PubMed=8878451; DOI=10.1111/j.1349-7006.1996.tb02118.x; PMCID=PMC5921198;
RA   Zhang S., Endo S., Koga H., Ichikawa T., Feng X., Onda K.,
RA   Washiyama K., Kumanishi T.;
RT   "A comparative study of glioma cell lines for p16, p15, p53 and p21
RT   gene alterations.";
RL   Jpn. J. Cancer Res. 87:900-907(1996).
//
RX   PubMed=10551321; DOI=10.1111/j.1349-7006.1999.tb00838.x; PMCID=PMC5926156;
RA   Zhang S.-J., Endo S., Ichikawa T., Yoshimura J., Onda K., Tanaka R.,
RA   Washiyama K., Kumanishi T.;
RT   "Rare-type mutations of MMAC1 tumor suppressor gene in human glioma
RT   cell lines and their tumors of origin.";
RL   Jpn. J. Cancer Res. 90:934-941(1999).
//
RX   PubMed=18415661; DOI=10.1007/s10014-007-0226-0;
RA   Tanaka Y., Zhang S.-J., Terasaki H., Koga H., Endo S., Usui H.,
RA   Washiyama K., Kumanishi T., Uematsu Y., Itakura T.;
RT   "Frequent and variable abnormalities in p14 tumor suppressor gene in
RT   glioma cell lines.";
RL   Brain Tumor Pathol. 25:9-17(2008).
//