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Cellosaurus HEK293SF-3F6 (CVCL_4V95)

[Text version]
Cell line name HEK293SF-3F6
Synonyms HEK293-SF-3F6; HEK 293SF-3F6; 293SF-3F6
Accession CVCL_4V95
Resource Identification Initiative To cite this cell line use: HEK293SF-3F6 (RRID:CVCL_4V95)
Comments Group: Patented cell line.
Group: Serum/protein free medium cell line.
Group: Vaccine production cell line.
Registration: International Depositary Authority, American Type Culture Collection (ATCC); CRL-12585.
Biotechnology: Used for the production of the CanSino Biologics Ebola virus vaccine (Trade name: Ad5-EBOV).
Biotechnology: Used for the production of the CanSino Biologics SARS-CoV-2 (COVID-19) vaccine (Trade name: Convidecia; also known as Ad5-nCOV) (DrugBank=DB15655).
Transformant: NCBI_TaxID; 28285; Adenovirus 5.
Derived from site: In situ; Fetal kidney; UBERON=UBERON_0002113.
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_4V94 (HEK293SF)
Sex of cell Female
Age at sampling Fetus
Category Transformed cell line
Web pages https://web.archive.org/web/20190105224206/http://www.nrc-cnrc.gc.ca/eng/solutions/licensing/10894.html

PubMed=10099373; DOI=10.1002/(SICI)1097-0290(19980905)59:5<567::AID-BIT6>3.0.CO;2-8
Cote J., Garnier A., Massie B., Kamen A.A.
Serum-free production of recombinant proteins and adenoviral vectors by 293SF-3F6 cells.
Biotechnol. Bioeng. 59:567-575(1998)

Cote J., Kamen A.A., Massie B.
Serum free production of recombinant proteins and adenoviral vectors.
Patent number US6210922, 03-Apr-2001

PubMed=31548015; DOI=10.1016/j.vaccine.2019.09.044
Gelinas J.-F., Azizi H., Kiesslich S., Lanthier S., Perdersen J., Chahal P.S., Ansorge S., Kobinger G.P., Gilbert R., Kamen A.A.
Production of rVSV-ZEBOV in serum-free suspension culture of HEK 293SF cells.
Vaccine 37:6624-6632(2019)

Cell line collections (Providers) ATCC; CRL-12585
Encyclopedic resources Wikidata; Q54882487
Entry history
Entry creation14-Dec-2015
Last entry update29-Jun-2023
Version number11