ID   HEK293SF-3F6
AC   CVCL_4V95
SY   HEK293-SF-3F6; HEK 293SF-3F6; 293SF-3F6
DR   ATCC; CRL-12585
DR   Wikidata; Q54882487
RX   Patent=US6210922;
RX   PubMed=10099373;
RX   PubMed=31548015;
WW   https://web.archive.org/web/20190105224206/http://www.nrc-cnrc.gc.ca/eng/solutions/licensing/10894.html
WW   https://www.canada.ca/en/national-research-council/news/2020/05/the-national-research-council-of-canada-and-cansino-biologics-inc-announce-collaboration-to-advance-vaccine-against-covid-19.html
CC   Group: Patented cell line.
CC   Group: Serum/protein free medium cell line.
CC   Group: Vaccine production cell line.
CC   Registration: International Depositary Authority, American Type Culture Collection (ATCC); CRL-12585.
CC   Biotechnology: Used for the production of the CanSino Biologics Ebola virus vaccine (Trade name: Ad5-EBOV).
CC   Biotechnology: Used for the production of the CanSino Biologics SARS-CoV-2 (COVID-19) vaccine (Trade name: Convidecia; also known as Ad5-nCOV) (DrugBank=DB15655).
CC   Transformant: NCBI_TaxID; 28285; Adenovirus 5.
CC   Derived from site: In situ; Fetal kidney; UBERON=UBERON_0002113.
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
HI   CVCL_4V94 ! HEK293SF
SX   Female
AG   Fetus
CA   Transformed cell line
DT   Created: 14-12-15; Last updated: 29-06-23; Version: 11
//
RX   Patent=US6210922;
RA   Cote J., Kamen A.A., Massie B.;
RT   "Serum free production of recombinant proteins and adenoviral
RT   vectors.";
RL   Patent number US6210922, 03-Apr-2001.
//
RX   PubMed=10099373; DOI=10.1002/(SICI)1097-0290(19980905)59:5<567::AID-BIT6>3.0.CO;2-8;
RA   Cote J., Garnier A., Massie B., Kamen A.A.;
RT   "Serum-free production of recombinant proteins and adenoviral vectors
RT   by 293SF-3F6 cells.";
RL   Biotechnol. Bioeng. 59:567-575(1998).
//
RX   PubMed=31548015; DOI=10.1016/j.vaccine.2019.09.044;
RA   Gelinas J.-F., Azizi H., Kiesslich S., Lanthier S., Perdersen J.,
RA   Chahal P.S., Ansorge S., Kobinger G.P., Gilbert R., Kamen A.A.;
RT   "Production of rVSV-ZEBOV in serum-free suspension culture of HEK
RT   293SF cells.";
RL   Vaccine 37:6624-6632(2019).
//