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Cellosaurus SKBR3-LAP[r] (CVCL_4V68)

[Text version]
Cell line name SKBR3-LAP[r]
Accession CVCL_4V68
Resource Identification Initiative To cite this cell line use: SKBR3-LAP[r] (RRID:CVCL_4V68)
Comments Population: Caucasian.
Selected for resistance to: ChEBI; CHEBI:49603; Lapatinib (Tykerb; Tyverb).
Derived from site: Metastatic; Pleural effusion; UBERON=UBERON_0000175.
Sequence variations
  • Gene deletion; HGNC; 1748; CDH1; Zygosity=Homozygous (from parent cell line).
  • Mutation; HGNC; 11998; TP53; Simple; p.Arg175His (c.524G>A); ClinVar=VCV000012374; Zygosity=Homozygous (from parent cell line).
Disease Breast adenocarcinoma (NCIt: C5214)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_0033 (SK-BR-3)
Sex of cell Female
Age at sampling 43Y
Category Cancer cell line
Web pages http://www.chemoscreen.com/product/skbr3-lapr-dna
Cell line databases/resources cancercelllines; CVCL_4V68
Encyclopedic resources Wikidata; Q54954667
Entry history
Entry creation14-Dec-2015
Last entry update05-Oct-2023
Version number12