Cellosaurus cell line HL/CAFdA20 (CVCL

Cellosaurus HL/CAFdA20 (CVCL_4V55)

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Cell line name

HL/CAFdA20

Accession

CVCL_4V55

Resource Identification Initiative

To cite this cell line use: HL/CAFdA20 (RRID:CVCL_4V55)

Comments

Population: Caucasian.
Selected for resistance to: ChEBI; CHEBI_681569; Clofarabine (CAFdA).
Derived from site: In situ; Peripheral blood; UBERON=UBERON_0000178.

Sequence variations

Gene deletion; HGNC; HGNC:11998; TP53; Zygosity=Homozygous (from parent cell line).
Mutation; HGNC; HGNC:1787; CDKN2A; Simple; p.Arg80Ter (c.238C>T) (p.Pro94Leu, c.281C>T); ClinVar=VCV000009409; Zygosity=Homozygous (from parent cell line).
Mutation; HGNC; HGNC:7989; NRAS; Simple; p.Gln61Leu (c.182A>T); ClinVar=VCV000375874; Zygosity=Heterozygous (from parent cell line).

Disease

Adult acute myeloid leukemia with maturation (NCIt: C7961)
Acute myeloblastic leukemia with maturation (ORDO: Orphanet_98834)

Species of origin

Homo sapiens (Human) (NCBI Taxonomy: 9606)

Hierarchy

Parent: CVCL_0002 (HL-60)
Children:

CVCL_4V56 (HL/CAFdA80)

Sex of cell

Female

Age at sampling

36Y