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Cellosaurus Sf900+ (CVCL_4U10)

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Cell line name Sf900+
Synonyms expresSF+; expressSF+; express SF+; Express Sf+; Sf+
Accession CVCL_4U10
Resource Identification Initiative To cite this cell line use: Sf900+ (RRID:CVCL_4U10)
Comments Group: Insect cell line.
Group: Patented cell line.
Group: Recombinant protein production insect cell line.
Group: Vaccine production cell line.
Registration: International Depositary Authority, American Type Culture Collection (ATCC); CRL-12579.
Biotechnology: Used for the production of the porcine circovirus type 2 (PCV2) vaccine CircoFLEX. Used to produce the PCV2 ORF2 capsid protein (PubMed=29133148).
Derived from site: In situ; Ovary; UBERON=UBERON_0000992.
Species of origin Spodoptera frugiperda (Fall armyworm) (NCBI Taxonomy: 7108)
Hierarchy Parent: CVCL_0549 (Sf9)
Sex of cell Female
Age at sampling Pupal stage
Category Spontaneously immortalized cell line

Smith G.E., Foellmer H.G., Knell J., DeBartolomeis J., Voznesensky A.I.
Spodoptera frugiperda single cell suspension cell line in serum-free media, methods of producing and using.
Patent number US6103526, 15-Aug-2000

PubMed=18304705; DOI=10.1016/j.vaccine.2007.11.053
Fachinger V., Bischoff R., Ben Jedidia S., Saalmuller A., Elbers K.
The effect of vaccination against porcine circovirus type 2 in pigs suffering from porcine respiratory disease complex.
Vaccine 26:1488-1499(2008)

PubMed=22265860; DOI=10.1016/j.vaccine.2012.01.016
Cox M.M.J.
Recombinant protein vaccines produced in insect cells.
Vaccine 30:1759-1766(2012)

PubMed=23848607; DOI=10.1021/pr400329k
An Y.-M., Rininger J.A., Jarvis D.L., Jing X.-H., Ye Z.-P., Aumiller J.J., Eichelberger M.C., Cipollo J.F.
Comparative glycomics analysis of influenza Hemagglutinin (H5N1) produced in vaccine relevant cell platforms.
J. Proteome Res. 12:3707-3720(2013)

PubMed=29133148; DOI=10.1016/j.pep.2017.11.002
Geisler C., Jarvis D.L.
Adventitious viruses in insect cell lines used for recombinant protein expression.
Protein Expr. Purif. 144:25-32(2017)

Encyclopedic resources Wikidata; Q54953005
Entry history
Entry creation22-Sep-2015
Last entry update29-Jun-2023
Version number11