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Cellosaurus H69PR (CVCL_4T78)

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Cell line name H69PR
Accession CVCL_4T78
Resource Identification Initiative To cite this cell line use: H69PR (RRID:CVCL_4T78)
Comments Group: Patented cell line.
Registration: International Depositary Authority, American Type Culture Collection (ATCC); CRL-11350.
Population: Caucasian.
Derived from site: Metastatic; Pleural effusion; UBERON=UBERON_0000175.
Sequence variations
  • Mutation; HGNC; HGNC:8975; PIK3CA; Simple; p.Gly106_Arg108del (c.317_325delGGCAACCGT); Zygosity=Heterozygous (from parent cell line).
  • Mutation; HGNC; HGNC:9884; RB1; Simple; p.Glu748Ter (c.2242G>T); ClinVar=VCV000013078; Zygosity=Homozygous (from parent cell line).
  • Mutation; HGNC; HGNC:11998; TP53; Simple; p.Glu171Ter (c.511G>T); ClinVar=VCV000634771; Zygosity=Homozygous (from parent cell line).
Disease Lung small cell carcinoma (NCIt: C4917)
Small cell lung cancer (ORDO: Orphanet_70573)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_3513 (NCI-H69AR)
Sex of cell Male
Age at sampling 55Y
Category Cancer cell line
Publications

PubMed=1314068; DOI=10.1038/bjc.1992.103; PMCID=PMC1977565
Susan P.C. Cole, Michael Joseph Pinkoski, Gabu Bhardwaj, Roger G. Deeley;
Elevated expression of annexin II (lipocortin II, p36) in a multidrug resistant small cell lung cancer cell line.
Br. J. Cancer 65:498-502(1992)

Patent=US5489519
Roger G. Deeley, Susan P.C. Cole;
Multidrug resistance protein.
Patent number US5489519, 06-Feb-1996

Cross-references
Cell line collections (Providers) ATCC; CRL-11350
Cell line databases/resources cancercelllines; CVCL_4T78
Encyclopedic resources Wikidata; Q54872206
Entry history
Entry creation22-Sep-2015
Last entry update19-Dec-2024
Version number15