ID   H69PR
AC   CVCL_4T78
DR   ATCC; CRL-11350
DR   cancercelllines; CVCL_4T78
DR   Wikidata; Q54872206
RX   Patent=US5489519;
RX   PubMed=1314068;
CC   Group: Patented cell line.
CC   Registration: International Depositary Authority, American Type Culture Collection (ATCC); CRL-11350.
CC   Population: Caucasian.
CC   Sequence variation: Mutation; HGNC; 8975; PIK3CA; Simple; p.Gly106_Arg108del (c.317_325delGGCAACCGT); Zygosity=Heterozygous (from parent cell line).
CC   Sequence variation: Mutation; HGNC; 9884; RB1; Simple; p.Glu748Ter (c.2242G>T); ClinVar=VCV000013078; Zygosity=Homozygous (from parent cell line).
CC   Sequence variation: Mutation; HGNC; 11998; TP53; Simple; p.Glu171Ter (c.511G>T); ClinVar=VCV000634771; Zygosity=Homozygous (from parent cell line).
CC   Derived from site: Metastatic; Pleural effusion; UBERON=UBERON_0000175.
DI   NCIt; C4917; Lung small cell carcinoma
DI   ORDO; Orphanet_70573; Small cell lung cancer
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
HI   CVCL_3513 ! H69AR
SX   Male
AG   55Y
CA   Cancer cell line
DT   Created: 22-09-15; Last updated: 05-10-23; Version: 14
//
RX   Patent=US5489519;
RA   Deeley R.G., Cole S.P.C.;
RT   "Multidrug resistance protein.";
RL   Patent number US5489519, 06-Feb-1996.
//
RX   PubMed=1314068; DOI=10.1038/bjc.1992.103;
RA   Cole S.P.C., Pinkoski M.J., Bhardwaj G., Deeley R.G.;
RT   "Elevated expression of annexin II (lipocortin II, p36) in a multidrug
RT   resistant small cell lung cancer cell line.";
RL   Br. J. Cancer 65:498-502(1992).
//