Cellosaurus logo
expasy logo

Cellosaurus SKG-II/LUC (CVCL_4J76)

[Text][XML][JSON]
Cell line name SKG-II/LUC
Synonyms SKG-II-LUC; SKG-II/luciferase
Accession CVCL_4J76
Resource Identification Initiative To cite this cell line use: SKG-II/LUC (RRID:CVCL_4J76)
Comments Population: Japanese.
Genetic integration: Method=Transfection/transduction; Gene=UniProtKB; P08659; Photinus pyralis firefly-type luciferase.
Transformant: NCBI_TaxID; 333761; Human papillomavirus type 18 (HPV18).
Derived from site: In situ; Uterus, cervix; UBERON=UBERON_0000002.
Sequence variations
  • Mutation; HGNC; HGNC:7773; NF2; Simple; p.Ser87Ter (c.260C>A); Zygosity=Unspecified (from parent cell line).
Disease Human papillomavirus-related cervical squamous cell carcinoma (NCIt: C27676)
Squamous cell carcinoma of the cervix uteri (ORDO: Orphanet_213767)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_2794 (SKG-II)
Sex of cell Female
Age at sampling 50Y
Category Cancer cell line
Publications

PubMed=12239455; DOI=10.1159/000063804
Yasushi Saga, Mitsuaki Suzuki, Hiroaki Mizukami, Masashi Urabe, Masakazu Fukushima, Keiya Ozawa, Ikuo Sato;
Enhanced expression of thymidylate synthase mediates resistance of uterine cervical cancer cells to radiation.
Oncology 63:185-191(2002)

PubMed=12845668; DOI=10.1002/ijc.11221
Yasushi Saga, Mitsuaki Suzuki, Hiroaki Mizukami, Takahiro Kohno, Yuji Takei, Masakazu Fukushima, Keiya Ozawa;
Overexpression of thymidylate synthase mediates desensitization for 5-fluorouracil of tumor cells.
Int. J. Cancer 106:324-326(2003)

Cross-references
Cell line databases/resources Cell_Model_Passport; SIDM01915
Encyclopedic resources Wikidata; Q54954729
Entry history
Entry creation22-Sep-2015
Last entry update14-Aug-2025
Version number15