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Cellosaurus SKG-II (CVCL_2794)

[Text version]
Cell line name SKG-II
Synonyms SKGII; SKG-2; SKG2
Accession CVCL_2794
Resource Identification Initiative To cite this cell line use: SKG-II (RRID:CVCL_2794)
Comments Part of: Cancer Dependency Map project (DepMap) (includes Cancer Cell Line Encyclopedia - CCLE).
Population: Japanese.
Doubling time: 31 hours (PubMed=10457904).
Transformant: NCBI_TaxID; 333761; Human papillomavirus type 18 (HPV18).
Derived from site: In situ; Uterus, cervix; UBERON=UBERON_0000002.
Sequence variations
  • Mutation; HGNC; HGNC:7773; NF2; Simple; p.Ser87Ter (c.260C>A); Zygosity=Unspecified (DepMap=ACH-001652).
HLA typing Source: PubMed=9023415
Class I
HLA-AA*24:02
Disease Human papillomavirus-related cervical squamous cell carcinoma (NCIt: C27676)
Squamous cell carcinoma of the cervix uteri (ORDO: Orphanet_213767)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Children:
CVCL_8159 (SKG-II-SF)CVCL_4J76 (SKG-II/LUC)CVCL_4J77 (SKG-II/TS)
Originate from same individual CVCL_VI91 ! SKG-IIB
Sex of cell Female
Age at sampling 50Y
Category Cancer cell line
STR profile Source(s): DepMap=ACH-001652; JCRB=IFO50309; PubMed=25877200

Markers:
AmelogeninX
CSF1PO12
D2S133820
D3S135815
D5S81812
D7S82011
D8S117913
D13S3178
D16S53911
D18S5118
D19S43314,16.2
D21S1128
FGA22
Penta D10
Penta E12
TH017,9 (DepMap=ACH-001652; JCRB=IFO50309)
9 (PubMed=25877200)
TPOX8,9
vWA16,18

Run an STR similarity search on this cell line
Publications

CLPUB00434
Isamu Ishiwata, Shiro Nozawa, Kazushige Kiguchi, Soju Kurihara, Hideo Okumura;
Establishment of human uterine cervical cancer cell line and comparative studies between normal and malignant uterine cervical cells in vitro.
Nihon Sanka Fujinka Gakkai Zasshi 30:731-738(1978)

PubMed=2429643; DOI=10.1111/j.1447-0756.1986.tb00192.x
Isamu Ishiwata, Chieko Ishiwata, Shiro Nozawa, Hiroshi Ishikawa;
CA125 production by gynecologic tumors in vitro and its modulation induced by dibutyl cyclic adenosine monophosphate.
Asia Oceania J. Obstet. Gynaecol. 12:285-290(1986)

PubMed=3029293; DOI=10.1099/0022-1317-68-2-583
Hiroshi Shirasawa, Yoshimi Tomita, Souei Sekiya, Hiroyoshi Takamizawa, Bunsiti Simizu;
Integration and transcription of human papillomavirus type 16 and 18 sequences in cell lines derived from cervical carcinomas.
J. Gen. Virol. 68:583-591(1987)

PubMed=2448191; DOI=10.1016/0090-8258(88)90151-5
Isamu Ishiwata, Chieko Ishiwata, Masayuki Soma, Isao Ono, Takenori Nakaguchi, Hiroshi Ishikawa;
Tumor angiogenic activity of gynecologic tumor cell lines on the chorioallantoic membrane.
Gynecol. Oncol. 29:87-93(1988)

CLPUB00481
Haruhiko Kuno, Touho Yoshida;
Detection of human papillomavirus types 16, 18, and 33 in cell lines derived from human genital organs by polymerase chain reaction.
Res. Commun. Inst. Ferment. 18:6-12(1997)

PubMed=9023415; DOI=10.1006/cimm.1996.1062
Naoko Seki, Tomoaki Hoshino, Megumi Kikuchi, Akihiro Hayashi, Kyogo Itoh;
HLA-A locus-restricted and tumor-specific CTLs in tumor-infiltrating lymphocytes of patients with non-small cell lung cancer.
Cell. Immunol. 175:101-110(1997)

PubMed=9436037
Masayuki Soma, Isamu Ishiwata, Chieko Ishiwata, Takenori Nakaguchi, Isao Ono, Kazushige Kiguchi, Hisashi Hashimoto, Toshiaki Tachibana, Hiroshi Ishikawa, Shiro Nozawa;
Tissue reconstruction of gynecologic tumor cells in the rotation culture system.
Hum. Cell 10:175-181(1997)

PubMed=9573483
Isamu Ishiwata, Yuko Tokieda, Chieko Ishiwata, Natsumi Okane, Megumi Iguchi, Kahei Sato, Hiroshi Ishikawa;
Effects of feeder cells (human cancer cell lines) on the development of mouse embryos by co-culture.
Hum. Cell 10:237-246(1997)

PubMed=10457904
Isamu Ishiwata, Tadashi Sudo, Kazushige Kiguchi, Hiroshi Ishikawa;
Tumor angiogenesis factors produced by cancer cells.
Hum. Cell 12:37-46(1999)

PubMed=25877200; DOI=10.1038/nature14397
Ma-Mie Yu, Suresh K. Selvaraj, May M.Y. Liang-Chu, Sahar Aghajani, Matthew Busse, Jean Yuan, Genee Lee, Franklin V. Peale, Christiaan Klijn, Richard Bourgon, Joshua S. Kaminker, Richard M. Neve;
A resource for cell line authentication, annotation and quality control.
Nature 520:307-311(2015)

Cross-references
Cell line collections (Providers) JCRB; IFO50309
JCRB; JCRB0171 - Discontinued
Cell line databases/resources Cell_Model_Passport; SIDM01854
DepMap; ACH-001652
Biological sample resources BioSample; SAMN03470893
BioSample; SAMN03472779
Encyclopedic resources Wikidata; Q54954727
Polymorphism and mutation databases Cosmic; 877460
Cosmic; 1152538
Entry history
Entry creation04-Apr-2012
Last entry update19-Dec-2024
Version number26