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Cellosaurus SKG-II (CVCL_2794)

[Text version]
Cell line name SKG-II
Synonyms SKGII; SKG-2; SKG2
Accession CVCL_2794
Resource Identification Initiative To cite this cell line use: SKG-II (RRID:CVCL_2794)
Comments Part of: Cancer Dependency Map project (DepMap) (includes Cancer Cell Line Encyclopedia - CCLE).
Population: Japanese.
Doubling time: 31 hours (PubMed=10457904).
Transformant: NCBI_TaxID; 333761; Human papillomavirus type 18 (HPV18).
Derived from site: In situ; Uterus, cervix; UBERON=UBERON_0000002.
Sequence variations
  • Mutation; HGNC; 7773; NF2; Simple; p.Ser87Ter (c.260C>A); Zygosity=Unspecified (DepMap=ACH-001652).
HLA typing Source: PubMed=9023415
Class I
Disease Human papillomavirus-related cervical squamous cell carcinoma (NCIt: C27676)
Squamous cell carcinoma of the cervix uteri (ORDO: Orphanet_213767)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Children:
Originate from same individual CVCL_VI91 ! SKG-IIB
Sex of cell Female
Age at sampling 50Y
Category Cancer cell line
STR profile Source(s): DepMap=ACH-001652; JCRB=IFO50309; PubMed=25877200

Penta D10
Penta E12
TH017,9 (DepMap=ACH-001652; JCRB=IFO50309)
9 (PubMed=25877200)

Run an STR similarity search on this cell line

Ishiwata I., Nozawa S., Kiguchi K., Kurihara S., Okumura H.
Establishment of human uterine cervical cancer cell line and comparative studies between normal and malignant uterine cervical cells in vitro.
Nihon Sanka Fujinka Gakkai Zasshi 30:731-738(1978)

PubMed=2429643; DOI=10.1111/j.1447-0756.1986.tb00192.x
Ishiwata I., Ishiwata C., Nozawa S., Ishikawa H.
CA125 production by gynecologic tumors in vitro and its modulation induced by dibutyl cyclic adenosine monophosphate.
Asia Oceania J. Obstet. Gynaecol. 12:285-290(1986)

PubMed=3029293; DOI=10.1099/0022-1317-68-2-583
Shirasawa H., Tomita Y., Sekiya S., Takamizawa H., Simizu B.
Integration and transcription of human papillomavirus type 16 and 18 sequences in cell lines derived from cervical carcinomas.
J. Gen. Virol. 68:583-591(1987)

PubMed=2448191; DOI=10.1016/0090-8258(88)90151-5
Ishiwata I., Ishiwata C., Soma M., Ono I., Nakaguchi T., Ishikawa H.
Tumor angiogenic activity of gynecologic tumor cell lines on the chorioallantoic membrane.
Gynecol. Oncol. 29:87-93(1988)

Kuno H., Yoshida T.
Detection of human papillomavirus types 16, 18, and 33 in cell lines derived from human genital organs by polymerase chain reaction.
Res. Commun. Inst. Ferment. Osaka 18:6-12(1997)

PubMed=9023415; DOI=10.1006/cimm.1996.1062
Seki N., Hoshino T., Kikuchi M., Hayashi A., Itoh K.
HLA-A locus-restricted and tumor-specific CTLs in tumor-infiltrating lymphocytes of patients with non-small cell lung cancer.
Cell. Immunol. 175:101-110(1997)

Soma M., Ishiwata I., Ishiwata C., Nakaguchi T., Ono I., Kiguchi K., Hashimoto H., Tachibana T., Ishikawa H., Nozawa S.
Tissue reconstruction of gynecologic tumor cells in the rotation culture system.
Hum. Cell 10:175-181(1997)

Ishiwata I., Tokieda Y., Ishiwata C., Okane N., Iguchi M., Sato K., Ishikawa H.
Effects of feeder cells (human cancer cell lines) on the development of mouse embryos by co-culture.
Hum. Cell 10:237-246(1997)

Ishiwata I., Sudo T., Kiguchi K., Ishikawa H.
Tumor angiogenesis factors produced by cancer cells.
Hum. Cell 12:37-46(1999)

PubMed=25877200; DOI=10.1038/nature14397
Yu M., Selvaraj S.K., Liang-Chu M.M.Y., Aghajani S., Busse M., Yuan J., Lee G., Peale F.V., Klijn C., Bourgon R., Kaminker J.S., Neve R.M.
A resource for cell line authentication, annotation and quality control.
Nature 520:307-311(2015)

Cell line collections (Providers) JCRB; IFO50309
JCRB; JCRB0171 - Discontinued
Cell line databases/resources Cell_Model_Passport; SIDM01854
DepMap; ACH-001652
Biological sample resources BioSample; SAMN03470893
BioSample; SAMN03472779
Encyclopedic resources Wikidata; Q54954727
Polymorphism and mutation databases Cosmic; 877460
Cosmic; 1152538
Entry history
Entry creation04-Apr-2012
Last entry update02-May-2024
Version number25