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Cellosaurus SKO-007 clone J3 (CVCL_4975)

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Cell line name SKO-007 clone J3
Synonyms Clone J3 of SKO-007
Accession CVCL_4975
Resource Identification Initiative To cite this cell line use: SKO-007 clone J3 (RRID:CVCL_4975)
Comments Group: Hybridoma fusion partner cell line.
Population: Caucasian.
Characteristics: Produces IgE lambda (from parent cell line).
Selected for resistance to: ChEBI; CHEBI_63486; 8-azaguanine.
Derived from site: In situ; Peripheral blood; UBERON=UBERON_0000178.
Cell type: Plasma cell; CL=CL_0000786.
Sequence variations
  • Mutation; HGNC; HGNC:1097; BRAF; Simple; p.Lys601Asn (c.1803A>T); ClinVar=VCV000376285; Zygosity=Heterozygous (from parent cell line).
  • Mutation; HGNC; HGNC:7329; MSH6; Simple; p.Gly141Asp (c.422G>A); ClinVar=VCV001491786; Zygosity=Heterozygous (from parent cell line).
  • Mutation; HGNC; HGNC:11998; TP53; Simple; p.Ala161Thr (c.481G>A); ClinVar=VCV000161518; Zygosity=Homozygous (from parent cell line).
  • Mutation; HGNC; HGNC:12033; TRAF3; Simple; p.Lys550Leufs*3 (c.1648_1649insT); Zygosity=Homozygous (from parent cell line).
Disease Plasma cell myeloma (NCIt: C3242)
Multiple myeloma (ORDO: Orphanet_29073)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_4974 (SKO-007)
Sex of cell Male
Age at sampling 53Y
Category Cancer cell line
STR profile Source(s): ATCC=CRL-8033-2

Markers:
AmelogeninX,Y
CSF1PO12,13
D5S81811,12
D7S82011,12
D13S31712
D16S53910
TH015,7
TPOX8
vWA17

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Cross-references
Cell line collections (Providers) ATCC; CRL-8033-2
Cell line databases/resources CLO; CLO_0009062
cancercelllines; CVCL_4975
Encyclopedic resources Wikidata; Q54954760
Entry history
Entry creation04-Apr-2012
Last entry update14-Aug-2025
Version number24