Cellosaurus cell line A2780/R (CVCL

Cross-references
Cell line name	A2780/R
Accession	CVCL_4862
Resource Identification Initiative	To cite this cell line use: A2780/R (RRID:CVCL_4862)
Comments	Population: African American. Selected for resistance to: ChEBI; CHEBI_48120; Anthracycline. Derived from site: In situ; Ovary; UBERON=UBERON_0000992.
Sequence variations	Mutation; HGNC; HGNC:795; ATM; Simple; p.Pro604Ser (c.1810C>T); ClinVar=VCV000127343; Zygosity=Unspecified (from parent cell line). Mutation; HGNC; HGNC:8975; PIK3CA; Simple; p.Glu365Lys (c.1093G>A); ClinVar=VCV000419222; Zygosity=Heterozygous (from parent cell line). Mutation; HGNC; HGNC:9588; PTEN; Simple; p.Lys128_Arg130del (c.383_391del9); Zygosity=Homozygous (from parent cell line). Mutation; HGNC; HGNC:17271; RRAS2; Simple; p.Gln72Leu (c.215A>T); ClinVar=VCV000009447; Zygosity=Homozygous (from parent cell line).
Disease	Ovarian endometrioid adenocarcinoma (NCIt: C7979) Endometrioid carcinoma of ovary (ORDO: Orphanet_454723)
Species of origin	Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy	Parent: CVCL_0134 (A2780)
Sex of cell	Female
Age at sampling	Age unspecified
Category	Cancer cell line
Cell line databases/resources	cancercelllines; CVCL_4862
Anatomy/cell type resources	BTO; BTO_0005130
Encyclopedic resources	Wikidata; Q54606605
Entry history
Entry creation	04-Apr-2012
Last entry update	10-Apr-2025
Version number	18