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Cellosaurus ARCaP (CVCL_4830)

[Text version]
Cell line name ARCaP
Synonyms MDA-PCa-1; MDA-Pca-1; MDA PCa 1; M.D. Anderson-Prostate Cancer-1
Accession CVCL_4830
Resource Identification Initiative To cite this cell line use: ARCaP (RRID:CVCL_4830)
Comments Population: Caucasian.
Caution: While some papers (PubMed=14518029; PubMed=14518030) believe that ARCaP and MDA-PCa-1 are two separate cell lines originating from the same patient, the current view is that ARCaP was renamed MDA-PCa-1 when further prostate cancer cell lines (MDA-PCa-2a/2b) were established at MD Anderson.
Derived from site: Metastatic; Ascites; UBERON=UBERON_0007795.
Sequence variations
Disease Prostate carcinoma (NCIt: C4863)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Children:
CVCL_E7VG (ARCaP clone IF3)CVCL_E7VH (ARCaP clone IIC11)CVCL_E7VI (ARCaP clone IID4)
CVCL_E7VJ (ARCaPE)CVCL_E7VK (ARCaPM)
Sex of cell Male
Age at sampling 83Y
Category Cancer cell line
STR profile Source(s): PubMed=14518029

Markers:
AmelogeninX,Y
D3S135815,16
D5S81810,11
D7S82010,11
D8S117910,12
D13S31711
D18S5115
D21S1129
FGA21
vWA18,19

Run an STR similarity search on this cell line
Web pages Info; CaP CLDb; -; https://web.archive.org/web/20160703200724/http://capcelllines.ca:80/details.asp?id=85
Publications

PubMed=8986779; DOI=10.1073/pnas.93.26.15152; PMCID=PMC26372
Hai-Yen E. Zhau, Shi-Ming Chang, Bao-Qi Chen, Yun-Ling Wang, Hong-Quan Zhang, Ching-Hai Kao, Qing-Xiang Amy Sang, Sen Pathak, Leland W.K. Chung;
Androgen-repressed phenotype in human prostate cancer.
Proc. Natl. Acad. Sci. U.S.A. 93:15152-15157(1996)

PubMed=12725112; DOI=10.1385/1-59259-372-0:21
Pamela J. Russell, Elizabeth A. Kingsley;
Human prostate cancer cell lines.
Methods Mol. Med. 81:21-39(2003)

PubMed=14518029; DOI=10.1002/pros.10290
Adrie van Bokhoven, Marileila Varella-Garcia, Christopher T. Korch, Widya U. Johannes, E. Erin Smith, Heidi L. Miller, Steven K. Nordeen, Gary J. Miller, M. Scott Lucia;
Molecular characterization of human prostate carcinoma cell lines.
Prostate 57:205-225(2003)

PubMed=14518030; DOI=10.1002/pros.10291
Adrie van Bokhoven, Aimee Caires, Michael Di Maria, Aline Passarini Schulte, M. Scott Lucia, Steven K. Nordeen, Gary J. Miller, Marileila Varella-Garcia;
Spectral karyotype (SKY) analysis of human prostate carcinoma cell lines.
Prostate 57:226-244(2003)

CLPUB00698
Adrie van Bokhoven;
Models for prostate cancer. Molecular characterization and critical appraisal of human prostate carcinoma cell lines.
Thesis PhD (2004); Katholieke Universiteit Nijmegen; Nijmegen; Netherlands

PubMed=15643172; DOI=10.1097/01.ju.0000141580.30910.57
Richard E. Sobel, Marianne D. Sadar;
Cell lines used in prostate cancer research: a compendium of old and new lines -- part 1.
J. Urol. 173:342-359(2005)

PubMed=16902972; DOI=10.1002/pros.20488
Jian-Chun Xu, Ruo-Xiang Wang, Zhi-Hui Xie, Valerie Odero-Marah, Sen Pathak, Asha S. Multani, Leland W.K. Chung, Hai-Yen E. Zhau;
Prostate cancer metastasis: role of the host microenvironment in promoting epithelial to mesenchymal transition and increased bone and adrenal gland metastasis.
Prostate 66:1664-1673(2006)

Cross-references
Cell line databases/resources cancercelllines; CVCL_4830
TOKU-E; 4101
Encyclopedic resources Wikidata; Q54750438
Polymorphism and mutation databases IARC_TP53; 18890
Entry history
Entry creation04-Apr-2012
Last entry update10-Apr-2025
Version number21