Cellosaurus logo
expasy logo

Cellosaurus DuPro-1 (CVCL_4738)

[Text version]
Cell line name DuPro-1
Synonyms DuPro; DUPRO
Accession CVCL_4738
Resource Identification Initiative To cite this cell line use: DuPro-1 (RRID:CVCL_4738)
Comments Problematic cell line: Contaminated. Shown to be a PC-3 derivative (PubMed=14518029; PubMed=20143388). Originally thought to originate from the metastasis in the left supraclavicular lymph node of a 58 year old patient with advanced prostate adenocarcinoma.
Registration: International Cell Line Authentication Committee, Register of Misidentified Cell Lines; ICLAC-00189.
Population: Caucasian.
Derived from site: Metastatic; Bone; UBERON=UBERON_0002481.
Sequence variations
  • Mutation; HGNC; 11998; TP53; Simple; p.Lys139Argfs*31 (c.414delC) (413delC); ClinVar=VCV000133281; Zygosity=Homozygous (PubMed=8510267).
Disease Prostate carcinoma (NCIt: C4863)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_0035 (PC-3)
Sex of cell Male
Age at sampling 62Y
Category Cancer cell line
Web pages https://iclac.org/wp-content/uploads/Cross-Contaminations_v13_distribution.xlsx

PubMed=1875519; DOI=10.1016/S0022-5347(17)37960-0
Gingrich J.R., Tucker J.A., Walther P.J., Day J.W., Poulton S.H.M., Webb K.S.
Establishment and characterization of a new human prostatic carcinoma cell line (DuPro-1).
J. Urol. 146:915-919(1991)

PubMed=8510267; DOI=10.1016/S0022-5347(17)35458-7
Effert P.J., McCoy R.H., Walther P.J., Liu E.T.-B.
p53 gene alterations in human prostate carcinoma.
J. Urol. 150:257-261(1993)

PubMed=14518029; DOI=10.1002/pros.10290
van Bokhoven A., Varella-Garcia M., Korch C.T., Johannes W.U., Smith E.E., Miller H.L., Nordeen S.K., Miller G.J., Lucia M.S.
Molecular characterization of human prostate carcinoma cell lines.
Prostate 57:205-225(2003)

PubMed=15643172; DOI=10.1097/01.ju.0000141580.30910.57
Sobel R.E., Sadar M.D.
Cell lines used in prostate cancer research: a compendium of old and new lines -- part 1.
J. Urol. 173:342-359(2005)

PubMed=20143388; DOI=10.1002/ijc.25242
Capes-Davis A., Theodosopoulos G., Atkin I., Drexler H.G., Kohara A., MacLeod R.A.F., Masters J.R.W., Nakamura Y., Reid Y.A., Reddel R.R., Freshney R.I.
Check your cultures! A list of cross-contaminated or misidentified cell lines.
Int. J. Cancer 127:1-8(2010)

Cell line databases/resources cancercelllines; CVCL_4738
Anatomy/cell type resources BTO; BTO:0004186
Biological sample resources BioSample; SAMN03151892
Chemistry resources ChEMBL-Cells; CHEMBL3307488
ChEMBL-Targets; CHEMBL614289
PubChem_Cell_line; CVCL_4738
Encyclopedic resources Wikidata; Q27972077
Polymorphism and mutation databases IARC_TP53; 2303
Entry history
Entry creation04-Apr-2012
Last entry update02-May-2024
Version number28