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Cellosaurus ALVA-101 (CVCL_4735)

[Text version]
Cell line name ALVA-101
Synonyms ALVA 101; ALVA101; American Lake VA-101
Accession CVCL_4735
Resource Identification Initiative To cite this cell line use: ALVA-101 (RRID:CVCL_4735)
Comments Problematic cell line: Contaminated. Shown to be a PC-3 derivative (PubMed=14518029; PubMed=20143388).
Registration: International Cell Line Authentication Committee, Register of Misidentified Cell Lines; ICLAC-00176.
Population: Caucasian.
Doubling time: 24 hours (PubMed=8561862).
Derived from site: Metastatic; Bone; UBERON=UBERON_0002481.
Sequence variations
  • Mutation; HGNC; 11998; TP53; Simple; p.Lys139Argfs*31 (c.414delC) (413delC); ClinVar=VCV000133281; Zygosity=Homozygous (from parent cell line).
Disease Prostate carcinoma (NCIt: C4863)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_0035 (PC-3)
Sex of cell Male
Age at sampling 62Y
Category Cancer cell line
Web pages https://web.archive.org/web/20160703200517/http://capcelllines.ca:80/details.asp?id=170

PubMed=1958578; DOI=10.1016/0960-0760(91)90309-S
Plymate S.R., Loop S.M., Hoop R.C., Wiren K.M., Ostenson R.C., Hryb D.J., Rosner W.
Effects of sex hormone binding globulin (SHBG) on human prostatic carcinoma.
J. Steroid Biochem. Mol. Biol. 40:833-839(1991)

PubMed=8561862; DOI=10.1002/(SICI)1098-2744(199601)15:1<18::AID-MC4>3.0.CO;2-O
Mehta P.P., Lokeshwar B.L., Schiller P.C., Bendix M.V., Ostenson R.C., Howard G.A., Roos B.A.
Gap-junctional communication in normal and neoplastic prostate epithelial cells and its regulation by cAMP.
Mol. Carcinog. 15:18-32(1996)

PubMed=9018337; DOI=10.1002/(SICI)1097-0045(19970101)30:1<58::AID-PROS9>3.0.CO;2-H
Webber M.M., Bello D., Quader S.T.A.
Immortalized and tumorigenic adult human prostatic epithelial cell lines: characteristics and applications Part 2. Tumorigenic cell lines.
Prostate 30:58-64(1997)

PubMed=12725112; DOI=10.1385/1-59259-372-0:21
Russell P.J., Kingsley E.A.
Human prostate cancer cell lines.
Methods Mol. Med. 81:21-39(2003)

PubMed=14518029; DOI=10.1002/pros.10290
van Bokhoven A., Varella-Garcia M., Korch C.T., Johannes W.U., Smith E.E., Miller H.L., Nordeen S.K., Miller G.J., Lucia M.S.
Molecular characterization of human prostate carcinoma cell lines.
Prostate 57:205-225(2003)

PubMed=15643172; DOI=10.1097/01.ju.0000141580.30910.57
Sobel R.E., Sadar M.D.
Cell lines used in prostate cancer research: a compendium of old and new lines -- part 1.
J. Urol. 173:342-359(2005)

PubMed=20143388; DOI=10.1002/ijc.25242
Capes-Davis A., Theodosopoulos G., Atkin I., Drexler H.G., Kohara A., MacLeod R.A.F., Masters J.R.W., Nakamura Y., Reid Y.A., Reddel R.R., Freshney R.I.
Check your cultures! A list of cross-contaminated or misidentified cell lines.
Int. J. Cancer 127:1-8(2010)

Cell line databases/resources cancercelllines; CVCL_4735
Biological sample resources BioSample; SAMN03151888
Encyclopedic resources Wikidata; Q54749372
Entry history
Entry creation04-Apr-2012
Last entry update02-May-2024
Version number25