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Cellosaurus ALVA-101 (CVCL_4735)

[Text version]
Cell line name ALVA-101
Synonyms ALVA 101; ALVA101; American Lake VA-101
Accession CVCL_4735
Resource Identification Initiative To cite this cell line use: ALVA-101 (RRID:CVCL_4735)
Comments Problematic cell line: Contaminated. Shown to be a PC-3 derivative (PubMed=14518029; PubMed=20143388).
Registration: International Cell Line Authentication Committee, Register of Misidentified Cell Lines; ICLAC-00176.
Population: Caucasian.
Doubling time: 24 hours (PubMed=8561862).
Derived from site: Metastatic; Bone; UBERON=UBERON_0002481.
Sequence variations
  • Mutation; HGNC; HGNC:11998; TP53; Simple; p.Lys139Argfs*31 (c.414delC) (413delC); ClinVar=VCV000133281; Zygosity=Homozygous (from parent cell line).
Disease Prostate carcinoma (NCIt: C4863)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_0035 (PC-3)
Sex of cell Male
Age at sampling 62Y
Category Cancer cell line
Web pages Info; CaP CLDb; -; https://web.archive.org/web/20160703200517/http://capcelllines.ca:80/details.asp?id=170
Info; ICLAC; -; https://iclac.org/wp-content/uploads/Cross-Contaminations_v13_distribution.xlsx
Publications

PubMed=1958578; DOI=10.1016/0960-0760(91)90309-S
Stephen Rex Plymate, Steven M. Loop, Rita Caporicci Hoop, Kristine M. Wiren, Richard C. Ostenson, Daniel J. Hryb, William Rosner;
Effects of sex hormone binding globulin (SHBG) on human prostatic carcinoma.
J. Steroid Biochem. Mol. Biol. 40:833-839(1991)

PubMed=8561862; DOI=10.1002/(SICI)1098-2744(199601)15:1<18::AID-MC4>3.0.CO;2-O
Parmender P. Mehta, Balakrishna L. Lokeshwar, Paul C. Schiller, Marcelo V. Bendix, Richard C. Ostenson, Guy A. Howard, Bernard A. Roos;
Gap-junctional communication in normal and neoplastic prostate epithelial cells and its regulation by cAMP.
Mol. Carcinog. 15:18-32(1996)

PubMed=9018337; DOI=10.1002/(SICI)1097-0045(19970101)30:1<58::AID-PROS9>3.0.CO;2-H
Mukta M. Webber, Diana Bello, Salmaan T.A. Quader;
Immortalized and tumorigenic adult human prostatic epithelial cell lines: characteristics and applications Part 2. Tumorigenic cell lines.
Prostate 30:58-64(1997)

PubMed=12725112; DOI=10.1385/1-59259-372-0:21
Pamela J. Russell, Elizabeth A. Kingsley;
Human prostate cancer cell lines.
Methods Mol. Med. 81:21-39(2003)

PubMed=14518029; DOI=10.1002/pros.10290
Adrie van Bokhoven, Marileila Varella-Garcia, Christopher T. Korch, Widya U. Johannes, E. Erin Smith, Heidi L. Miller, Steven K. Nordeen, Gary J. Miller, M. Scott Lucia;
Molecular characterization of human prostate carcinoma cell lines.
Prostate 57:205-225(2003)

PubMed=15643172; DOI=10.1097/01.ju.0000141580.30910.57
Richard E. Sobel, Marianne D. Sadar;
Cell lines used in prostate cancer research: a compendium of old and new lines -- part 1.
J. Urol. 173:342-359(2005)

PubMed=20143388; DOI=10.1002/ijc.25242
Amanda Capes-Davis, George Theodosopoulos, Isobel Atkin, Hans Gunther Drexler, Arihiro Kohara, Roderick A.F. MacLeod, John R.W. Masters, Yukio Nakamura, Yvonne A. Reid, Roger Robert Reddel, Robert Ian Freshney;
Check your cultures! A list of cross-contaminated or misidentified cell lines.
Int. J. Cancer 127:1-8(2010)

Cross-references
Cell line databases/resources cancercelllines; CVCL_4735
Biological sample resources BioSample; SAMN03151888
Encyclopedic resources Wikidata; Q54749372
Entry history
Entry creation04-Apr-2012
Last entry update10-Apr-2025
Version number27