ID   ALVA-101
AC   CVCL_4735
SY   ALVA 101; ALVA101; American Lake VA-101
DR   BioSample; SAMN03151888
DR   cancercelllines; CVCL_4735
DR   Wikidata; Q54749372
RX   PubMed=1958578;
RX   PubMed=8561862;
RX   PubMed=9018337;
RX   PubMed=12725112;
RX   PubMed=14518029;
RX   PubMed=15643172;
RX   PubMed=20143388;
WW   Info; CaP CLDb; -; https://web.archive.org/web/20160703200517/http://capcelllines.ca:80/details.asp?id=170
WW   Info; ICLAC; -; https://iclac.org/wp-content/uploads/Cross-Contaminations_v13_distribution.xlsx
CC   Problematic cell line: Contaminated. Shown to be a PC-3 derivative (PubMed=14518029; PubMed=20143388).
CC   Registration: International Cell Line Authentication Committee, Register of Misidentified Cell Lines; ICLAC-00176.
CC   Population: Caucasian.
CC   Doubling time: 24 hours (PubMed=8561862).
CC   Sequence variation: Mutation; HGNC; HGNC:11998; TP53; Simple; p.Lys139Argfs*31 (c.414delC) (413delC); ClinVar=VCV000133281; Zygosity=Homozygous (from parent cell line).
CC   Derived from site: Metastatic; Bone; UBERON=UBERON_0002481.
DI   NCIt; C4863; Prostate carcinoma
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
HI   CVCL_0035 ! PC-3
SX   Male
AG   62Y
CA   Cancer cell line
DT   Created: 04-04-12; Last updated: 10-04-25; Version: 27
//
RX   PubMed=9018337; DOI=10.1002/(SICI)1097-0045(19970101)30:1<58::AID-PROS9>3.0.CO;2-H;
RA   Webber, Mukta M.
RA   Bello, Diana
RA   Quader, Salmaan T.A.
RT   "Immortalized and tumorigenic adult human prostatic epithelial cell
RT   lines: characteristics and applications Part 2. Tumorigenic cell
RT   lines.";
RL   Prostate 30:58-64(1997).
//
RX   PubMed=15643172; DOI=10.1097/01.ju.0000141580.30910.57;
RA   Sobel, Richard E.
RA   Sadar, Marianne D.
RT   "Cell lines used in prostate cancer research: a compendium of old and
RT   new lines -- part 1.";
RL   J. Urol. 173:342-359(2005).
//
RX   PubMed=12725112; DOI=10.1385/1-59259-372-0:21;
RA   Russell, Pamela Joan
RA   Kingsley, Elizabeth A.
RT   "Human prostate cancer cell lines.";
RL   Methods Mol. Med. 81:21-39(2003).
//
RX   PubMed=14518029; DOI=10.1002/pros.10290;
RA   van Bokhoven, Adrie
RA   Varella-Garcia, Marileila
RA   Korch, Christopher T.
RA   Johannes, Widya U.
RA   Smith, E. Erin
RA   Miller, Heidi L.
RA   Nordeen, Steven K.
RA   Miller, Gary J.
RA   Lucia, Marshall Scott
RT   "Molecular characterization of human prostate carcinoma cell lines.";
RL   Prostate 57:205-225(2003).
//
RX   PubMed=8561862; DOI=10.1002/(SICI)1098-2744(199601)15:1<18::AID-MC4>3.0.CO;2-O;
RA   Mehta, Parmender P.
RA   Lokeshwar, Balakrishna L.
RA   Schiller, Paul C.
RA   Bendix, Marcelo Vianna
RA   Ostenson, Richard C.
RA   Howard, Guy A.
RA   Roos, Bernard Allen
RT   "Gap-junctional communication in normal and neoplastic prostate
RT   epithelial cells and its regulation by cAMP.";
RL   Mol. Carcinog. 15:18-32(1996).
//
RX   PubMed=20143388; DOI=10.1002/ijc.25242;
RA   Capes-Davis, Amanda
RA   Theodosopoulos, George
RA   Atkin, Isobel
RA   Drexler, Hans Gunther
RA   Kohara, Arihiro
RA   MacLeod, Roderick A.F.
RA   Masters, John R.W.
RA   Nakamura, Yukio
RA   Reid, Yvonne A.
RA   Reddel, Roger Robert
RA   Freshney, Robert Ian
RT   "Check your cultures! A list of cross-contaminated or misidentified
RT   cell lines.";
RL   Int. J. Cancer 127:1-8(2010).
//
RX   PubMed=1958578; DOI=10.1016/0960-0760(91)90309-S;
RA   Plymate, Stephen Rex
RA   Loop, Steven M.
RA   Hoop, Rita Caporicci
RA   Wiren, Kristine M.
RA   Ostenson, Richard C.
RA   Hryb, Daniel J.
RA   Rosner, William
RT   "Effects of sex hormone binding globulin (SHBG) on human prostatic
RT   carcinoma.";
RL   J. Steroid Biochem. Mol. Biol. 40:833-839(1991).
//