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Cellosaurus NMFH-1 [RCB] (CVCL_4661)

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Cell line name NMFH-1 [RCB]
Synonyms NMFH1
Accession CVCL_4661
Resource Identification Initiative To cite this cell line use: NMFH-1 [RCB] (RRID:CVCL_4661)
Comments Population: Japanese.
Doubling time: 46 hours (Note=At 50th passage), 42 hours (Note=At 100th passage) (PubMed=16080955); 44 hours (PubMed=19335880).
Caution: There seem to be two NMFH-1 cell lines, both from myxofibrosarcomas (malignant fibrous histiocytomas). One from Niigata University (Kawashima H. et al) established from a 89 year old male patient and distributed by RCB and one from Shimada Y. established from a 43 year old male patient and distributed by JCRB. The two cell lines have very different STR profiles.
Derived from site: In situ; Knee, hypodermis; UBERON=UBERON_0001465+UBERON_0002072.
Disease Myxofibrosarcoma (NCIt: C6496)
Myxofibrosarcoma (ORDO: Orphanet_79105)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell Male
Age at sampling 89Y
Category Cancer cell line
STR profile Source(s): RCB=RCB2346

Markers:
AmelogeninX,Y
CSF1PO13,14
D5S81810,12
D7S82011
D13S3178,11
D16S53912
TH019
TPOX8,10
vWA14,18

Run an STR similarity search on this cell line
Publications

PubMed=15173092; DOI=10.1158/1078-0432.CCR-03-0345
Wen-Guang Gu, Akira Ogose, Hiroyuki Kawashima, Masayuki Ito, Tomoyuki Ito, Atsushi Matsuba, Hiroshi Kitahara, Tetsuo Hotta, Kunihiko Tokunaga, Hiroshi Hatano, Tetsuro Morita ...Show all 16 authors... , Sayuri Urakawa, Tatsuya Yoshizawa, Hiroyuki Kawashima, Ryozo Kuwano, Naoto Endo; Show fewer authors
High-level expression of the coxsackievirus and adenovirus receptor messenger RNA in osteosarcoma, Ewing's sarcoma, and benign neurogenic tumors among musculoskeletal tumors.
Clin. Cancer Res. 10:3831-3838(2004)

PubMed=16080955; DOI=10.1016/j.cancergencyto.2005.02.003
Hiroyuki Kawashima, Akira Ogose, Wen-Guang Gu, Jun Nishio, Naoko Kudo, Naoki Kondo, Tetsuo Hotta, Hajime Umezu, Tsuyoshi Tohyama, Hirokazu Nishijima, Hiroshi Iwasaki, Naoto Endo;
Establishment and characterization of a novel myxofibrosarcoma cell line.
Cancer Genet. Cytogenet. 161:28-35(2005)

PubMed=19335880; DOI=10.1186/1756-9966-28-44; PMCID=PMC2669054
Takashi Ariizumi, Akira Ogose, Hiroyuki Kawashima, Tetsuo Hotta, Hajime Umezu, Naoto Endo;
Multinucleation followed by an acytokinetic cell division in myxofibrosarcoma with giant cell proliferation.
J. Exp. Clin. Cancer Res. 28:44.1-44.6(2009)

PubMed=25760144; DOI=10.3892/or.2015.3842
De-Jian Li, Tao Zhang, Wen-Guang Gu, Peng Li, Xiang-Yang Cheng, Tie-Jun Tong, Wen-Bo Wang;
The ALDH1(+) subpopulation of the human NMFH-1 cell line exhibits cancer stem-like characteristics.
Oncol. Rep. 33:2291-2298(2015)

Cross-references
Cell line collections (Providers) RCB; RCB2346
Cell line databases/resources CLO; CLO_0050023
Biological sample resources BioSample; SAMN03471964
Encyclopedic resources Wikidata; Q54930837
Gene expression databases FANTOM5_SSTAR; 10684-109E9
Polymorphism and mutation databases Cosmic; 1172182
Entry history
Entry creation04-Apr-2012
Last entry update27-Nov-2025
Version number22