ID   NMFH-1 [RCB]
AC   CVCL_4661
SY   NMFH1
DR   CLO; CLO_0050023
DR   BioSample; SAMN03471964
DR   Cosmic; 1172182
DR   RCB; RCB2346
DR   Wikidata; Q54930837
RX   PubMed=15173092;
RX   PubMed=16080955;
RX   PubMed=19335880;
RX   PubMed=25760144;
CC   Population: Japanese.
CC   Doubling time: 46 hours (Note=At 50th passage), 42 hours (Note=At 100th passage) (PubMed=16080955).
CC   Caution: There seem to be two NMFH-1 cell lines, both from myxofibrosarcomas (malignant fibrous histiocytomas). One from Niigata University (Kawashima H. et al) established from a 89 year old male patient and distributed by RCB and one from Shimada Y. established from a 43 year old male patient and distributed by JCRB. The two cell lines have very different STR profiles.
CC   Derived from site: In situ; Knee, hypodermis; UBERON=UBERON_0001465+UBERON_0002072.
ST   Source(s): RCB=RCB2346
ST   Amelogenin: X,Y
ST   CSF1PO: 13,14
ST   D13S317: 8,11
ST   D16S539: 12
ST   D5S818: 10,12
ST   D7S820: 11
ST   TH01: 9
ST   TPOX: 8,10
ST   vWA: 14,18
DI   NCIt; C6496; Myxofibrosarcoma
DI   ORDO; Orphanet_79105; Myxofibrosarcoma
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
SX   Male
AG   89Y
CA   Cancer cell line
DT   Created: 04-04-12; Last updated: 02-05-24; Version: 20
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RX   PubMed=15173092; DOI=10.1158/1078-0432.CCR-03-0345;
RA   Gu W.-G., Ogose A., Kawashima H., Ito M., Ito T., Matsuba A.,
RA   Kitahara H., Hotta T., Tokunaga K., Hatano H., Morita T., Urakawa S.,
RA   Yoshizawa T., Kawashima H., Kuwano R., Endo N.;
RT   "High-level expression of the coxsackievirus and adenovirus receptor
RT   messenger RNA in osteosarcoma, Ewing's sarcoma, and benign neurogenic
RT   tumors among musculoskeletal tumors.";
RL   Clin. Cancer Res. 10:3831-3838(2004).
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RX   PubMed=16080955; DOI=10.1016/j.cancergencyto.2005.02.003;
RA   Kawashima H., Ogose A., Gu W.-G., Nishio J., Kudo N., Kondo N., Hotta T.,
RA   Umezu H., Tohyama T., Nishijima H., Iwasaki H., Endo N.;
RT   "Establishment and characterization of a novel myxofibrosarcoma cell
RT   line.";
RL   Cancer Genet. Cytogenet. 161:28-35(2005).
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RX   PubMed=19335880; DOI=10.1186/1756-9966-28-44;
RA   Ariizumi T., Ogose A., Kawashima H., Hotta T., Umezu H., Endo N.;
RT   "Multinucleation followed by an acytokinetic cell division in
RT   myxofibrosarcoma with giant cell proliferation.";
RL   J. Exp. Clin. Cancer Res. 28:44.1-44.6(2009).
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RX   PubMed=25760144; DOI=10.3892/or.2015.3842;
RA   Li D.-J., Zhang T., Gu W.-G., Li P., Cheng X.-Y., Tong T.-J., Wang W.-B.;
RT   "The ALDH1(+) subpopulation of the human NMFH-1 cell line exhibits
RT   cancer stem-like characteristics.";
RL   Oncol. Rep. 33:2291-2298(2015).
//