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Cellosaurus ELT3 (CVCL_4616)

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Cell line name ELT3
Synonyms ELT-3; ELT 3; Eker Leiomyoma Tumor-3
Accession CVCL_4616
Resource Identification Initiative To cite this cell line use: ELT3 (RRID:CVCL_4616)
Sequence variations
  • Mutation; RGD; 3908; Tsc2; Simple; p.Val1272fs; Zygosity=Heterozygous; Note=Insertion of a 5 kb retrotransposon (from inference of genetic background of other Eker-derived cell lines).
Disease Rat leiomyoma (NCIt: C60426)
Species of origin Rattus norvegicus (Rat) (NCBI Taxonomy: 10116)
Breed/subspecies: Eker x Long-Evans; RS=RS_0000385+RS_0000347.
Hierarchy Children:
CVCL_F0KL (ELT3 TSC2)
Sex of cell Female
Age at sampling 11-19M
Category Cancer cell line
Publications

PubMed=7539981; PMCID=PMC1870894
Susan R. Howe, Marco M. Gottardis, Jeffrey Ira Everitt, Thomas L. Goldsworthy, Douglas C. Wolf, Cheryl Lyn Walker;
Rodent model of reproductive tract leiomyomata. Establishment and characterization of tumor-derived cell lines.
Am. J. Pathol. 146:1568-1579(1995)

PubMed=15039427; DOI=10.1074/jbc.M401912200
Geraldine A. Finlay, Brian York, Richard H. Karas, Barry Lee Fanburg, Hong-Bing Zhang, David Joseph Kwiatkowski, Daniel J. Noonan;
Estrogen-induced smooth muscle cell growth is regulated by tuberin and associated with altered activation of platelet-derived growth factor receptor-beta and ERK-1/2.
J. Biol. Chem. 279:23114-23122(2004)

Cross-references
Cell line collections (Providers) ATCC; CRL-3371
Anatomy/cell type resources BTO; BTO_0003253
Encyclopedic resources Wikidata; Q54832257
Entry history
Entry creation04-Apr-2012
Last entry update14-Aug-2025
Version number14