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Cellosaurus CHO-DXB11 B13-24 (CVCL_4583)

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Cell line name CHO-DXB11 B13-24
Synonyms B13-24
Accession CVCL_4583
Resource Identification Initiative To cite this cell line use: CHO-DXB11 B13-24 (RRID:CVCL_4583)
Comments Group: Patented cell line.
Registration: International Depositary Authority, American Type Culture Collection (ATCC); CRL-11397.
Characteristics: Transfected with Ig heavy and light chain of humanized version of mAB produced by hybridoma 23F2g (Cellosaurus=CVCL_4W87).
Genetic integration: Method=Transfection; Gene=UniProtKB; P00552; Klebsiella pneumoniae transposon Tn5 neo.
Transformant: ChEBI; CHEBI_23994; Ethyl methanesulfonate (Methylsulfonic acid ethyl ester; MSEE).
Transformant: NCIt; C44386; Gamma radiation.
Derived from site: In situ; Ovary; UBERON=UBERON_0000992.
Cell type: Epithelial cell of ovary; CL=CL_2000064.
Sequence variations
  • Gene deletion; UniProtKB; Q2MH30; Dhfr; Zygosity=Heterozygous (from parent cell line).
  • Mutation; UniProtKB; Q2MH30; Dhfr; Simple; p.Thr137Arg (c.410G>C); Zygosity=Heterozygous (from parent cell line).
Species of origin Cricetulus griseus (Chinese hamster) (Cricetulus barabensis griseus) (NCBI Taxonomy: 10029)
Hierarchy Parent: CVCL_1977 (CHO-DXB11)
Sex of cell Female
Age at sampling Adult
Category Transformed cell line
Publications

Patent=US5854070
Lynn M. Rose;
Murine and humanized 23F2G antibodies and cell lines expressing said antibodies.
Patent number US5854070, 29-Dec-1998

Cross-references
Cell line collections (Providers) ATCC; CRL-11397
Cell line databases/resources CLO; CLO_0001787
Encyclopedic resources Wikidata; Q54752337
Entry history
Entry creation04-Apr-2012
Last entry update14-Aug-2025
Version number14