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Cellosaurus IB3-1/S9 (CVCL_4461)

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Cell line name IB3-1/S9
Synonyms S9
Accession CVCL_4461
Resource Identification Initiative To cite this cell line use: IB3-1/S9 (RRID:CVCL_4461)
Comments Characteristics: Stably transduced to achieve low-level expression of full-length wild-type CFTR.
Genetic integration: Method=Transduction; Gene=HGNC; HGNC:1884; CFTR.
Transformant: Ad12-SV40 hybrid virus.
Omics: Metabolomics.
Disease Cystic fibrosis (NCIt: C2975)
Cystic fibrosis (ORDO: Orphanet_586)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_0338 (IB3-1)
Sex of cell Male
Age at sampling 7Y
Category Transformed cell line
STR profile Source(s): ATCC=CRL-2778

Markers:
AmelogeninX,Y
CSF1PO10,11
D5S81811,12,13
D7S82011,12
D13S3178,12,13
D16S5399,11
TH018,9.3
TPOX8,9
vWA15,18

Run an STR similarity search on this cell line
Publications

PubMed=1380129; DOI=10.1038/358581a0
Marie Egan, Terence R. Flotte, Sandra A. Afione, Rikki Solow, Pamela L. Zeitlin, Barrie J. Carter, William B. Guggino;
Defective regulation of outwardly rectifying Cl- channels by protein kinase A corrected by insertion of CFTR.
Nature 358:581-584(1992)

PubMed=15463957; DOI=10.1016/j.jcf.2004.05.040
Dieter C. Gruenert, Marjolaine Willems, Jean-Jacques Cassiman, Raymond A. Frizzell;
Established cell lines used in cystic fibrosis research.
J. Cyst. Fibros. 3:191-196(2004)

Cross-references
Cell line collections (Providers) ATCC; CRL-2778 - Discontinued
ATCC; JHU-53 - Discontinued
Cell line databases/resources CLO; CLO_0008935
Anatomy/cell type resources BTO; BTO_0004446
Biological sample resources BioSample; SAMN03471786
Chemistry resources ChEMBL-Cells; CHEMBL3307435
ChEMBL-Targets; CHEMBL614892
PubChem_Cell_line; CVCL_4461
Encyclopedic resources Wikidata; Q54897165
Metabolomic databases MetaboLights; MTBLS102
Entry history
Entry creation04-Apr-2012
Last entry update10-Apr-2025
Version number20