ID   IB3-1/S9
AC   CVCL_4461
SY   S9
DR   BTO; BTO_0004446
DR   CLO; CLO_0008935
DR   ATCC; CRL-2778
DR   ATCC; JHU-53
DR   BioSample; SAMN03471786
DR   ChEMBL-Cells; CHEMBL3307435
DR   ChEMBL-Targets; CHEMBL614892
DR   MetaboLights; MTBLS102
DR   PubChem_Cell_line; CVCL_4461
DR   Wikidata; Q54897165
RX   PubMed=1380129;
RX   PubMed=15463957;
CC   Characteristics: Stably transduced to achieve low-level expression of full-length wild-type CFTR.
CC   Genetic integration: Method=Transduction; Gene=HGNC; HGNC:1884; CFTR.
CC   Transformant: Ad12-SV40 hybrid virus.
CC   Omics: Metabolomics.
CC   Discontinued: ATCC; CRL-2778; true.
CC   Discontinued: ATCC; JHU-53; true.
ST   Source(s): ATCC=CRL-2778
ST   Amelogenin: X,Y
ST   CSF1PO: 10,11
ST   D13S317: 8,12,13
ST   D16S539: 9,11
ST   D5S818: 11,12,13
ST   D7S820: 11,12
ST   TH01: 8,9.3
ST   TPOX: 8,9
ST   vWA: 15,18
DI   NCIt; C2975; Cystic fibrosis
DI   ORDO; Orphanet_586; Cystic fibrosis
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
HI   CVCL_0338 ! IB3-1
SX   Male
AG   7Y
CA   Transformed cell line
DT   Created: 04-04-12; Last updated: 10-04-25; Version: 20
//
RX   PubMed=1380129; DOI=10.1038/358581a0;
RA   Egan, Marie
RA   Flotte, Terence R.
RA   Afione, Sandra A.
RA   Solow, Rikki
RA   Zeitlin, Pamela L.
RA   Carter, Barrie J.
RA   Guggino, William B.
RT   "Defective regulation of outwardly rectifying Cl- channels by protein
RT   kinase A corrected by insertion of CFTR.";
RL   Nature 358:581-584(1992).
//
RX   PubMed=15463957; DOI=10.1016/j.jcf.2004.05.040;
RA   Gruenert, Dieter C.
RA   Willems, Marjolaine
RA   Cassiman, Jean-Jacques
RA   Frizzell, Raymond A.
RT   "Established cell lines used in cystic fibrosis research.";
RL   J. Cyst. Fibros. 3:191-196(2004).
//