ID   IB3-1/S9
AC   CVCL_4461
SY   S9
DR   BTO; BTO:0004446
DR   CLO; CLO_0008935
DR   ATCC; CRL-2778
DR   ATCC; JHU-53
DR   BioSample; SAMN03471786
DR   ChEMBL-Cells; CHEMBL3307435
DR   ChEMBL-Targets; CHEMBL614892
DR   MetaboLights; MTBLS102
DR   PubChem_Cell_line; CVCL_4461
DR   Wikidata; Q54897165
RX   PubMed=1380129;
RX   PubMed=15463957;
CC   Characteristics: Stably transduced to achieve low-level expression of full-length wild-type CFTR.
CC   Transfected with: HGNC; 1884; CFTR.
CC   Transformant: Ad12-SV40 hybrid virus.
CC   Omics: Metabolome analysis.
CC   Discontinued: ATCC; CRL-2778; true.
CC   Discontinued: ATCC; JHU-53; true.
ST   Source(s): ATCC=CRL-2778
ST   Amelogenin: X,Y
ST   CSF1PO: 10,11
ST   D13S317: 8,12,13
ST   D16S539: 9,11
ST   D5S818: 11,12,13
ST   D7S820: 11,12
ST   TH01: 8,9.3
ST   TPOX: 8,9
ST   vWA: 15,18
DI   NCIt; C2975; Cystic fibrosis
DI   ORDO; Orphanet_586; Cystic fibrosis
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
HI   CVCL_0338 ! IB3-1
SX   Male
AG   7Y
CA   Transformed cell line
DT   Created: 04-04-12; Last updated: 02-05-24; Version: 17
//
RX   PubMed=1380129; DOI=10.1038/358581a0;
RA   Egan M., Flotte T.R., Afione S.A., Solow R., Zeitlin P.L., Carter B.J.,
RA   Guggino W.B.;
RT   "Defective regulation of outwardly rectifying Cl- channels by protein
RT   kinase A corrected by insertion of CFTR.";
RL   Nature 358:581-584(1992).
//
RX   PubMed=15463957; DOI=10.1016/j.jcf.2004.05.040;
RA   Gruenert D.C., Willems M., Cassiman J.-J., Frizzell R.A.;
RT   "Established cell lines used in cystic fibrosis research.";
RL   J. Cyst. Fibros. 3:191-196(2004).
//