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Cellosaurus Dami (CVCL_4360)

[Text version]
Cell line name Dami
Synonyms DAMI
Accession CVCL_4360
Resource Identification Initiative To cite this cell line use: Dami (RRID:CVCL_4360)
Comments Group: Patented cell line.
Problematic cell line: Contaminated. Shown to be a HEL derivative (PubMed=9166871; PubMed=9326259; PubMed=9447816; PubMed=10508494; PubMed=12592342; PubMed=20143388). Originally thought to originate from the peripheral blood of a 57 year old male patient with megakaryoblastic leukemia.
Registration: International Cell Line Authentication Committee, Register of Misidentified Cell Lines; ICLAC-00116.
Registration: International Depositary Authority, American Type Culture Collection (ATCC); CRL-9792.
Population: Caucasian.
Doubling time: 24-30 hours (Patent=US5128245).
Derived from site: In situ; Peripheral blood; UBERON=UBERON_0000178.
Sequence variations
  • Mutation; HGNC; 6192; JAK2; Simple; p.Val617Phe (c.1849G>T); ClinVar=VCV000014662; Zygosity=Homozygous (from parent cell line).
  • Mutation; HGNC; 11998; TP53; Simple; p.Met133Lys (c.398T>A); ClinVar=VCV002430159; Zygosity=Homozygous (from parent cell line).
Disease Erythroleukemia (NCIt: C7152)
Acute erythroid leukemia (ORDO: Orphanet_318)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_0001 (HEL)
Sex of cell Male
Age at sampling 30Y
Category Cancer cell line
STR profile Source(s): ATCC=CRL-9792; CCRID

AmelogeninX (CCRID)
X,Y (ATCC=CRL-9792)

Run an STR similarity search on this cell line
Web pages https://www.atcc.org/en/support/technical-support/faqs/dami-atcc-crl-9792

PubMed=3196874; DOI=10.1182/blood.V72.6.1968.1968
Greenberg S.M., Rosenthal D.S., Greeley T.A., Tantravahi R., Handin R.I.
Characterization of a new megakaryocytic cell line: the Dami cell.
Blood 72:1968-1977(1988)

Greenberg S.M., Handin R.I.
Establishment, characterization and differentiation of a new megakaryocytic cell line, the Dami cells.
Patent number US5128245, 07-Jul-1992

PubMed=9166871; DOI=10.1182/blood.V89.11.4238
Handin R.I.
DAMI cell line.
Blood 89:4238-4238(1997)

PubMed=9326259; DOI=10.1182/blood.V90.7.2850
MacLeod R.A.F., Dirks W.G., Drexler H.G.
Early contamination of the Dami cell line by HEL.
Blood 90:2850-2851(1997)

PubMed=9447816; DOI=10.1038/sj.leu.2400868
MacLeod R.A.F., Dirks W.G., Reid Y.A., Hay R.J., Drexler H.G.
Identity of original and late passage Dami megakaryocytes with HEL erythroleukemia cells shown by combined cytogenetics and DNA fingerprinting.
Leukemia 11:2032-2038(1997)

PubMed=10508494; DOI=10.1002/(SICI)1097-0215(19991112)83:4<555::AID-IJC19>3.0.CO;2-2
MacLeod R.A.F., Dirks W.G., Matsuo Y., Kaufmann M., Milch H., Drexler H.G.
Widespread intraspecies cross-contamination of human tumor cell lines arising at source.
Int. J. Cancer 83:555-563(1999)

PubMed=11021758; DOI=10.1038/sj.leu.2401891
Majka M., Rozmyslowicz T., Honczarenko M., Ratajczak J., Wasik M.A., Gaulton G.N., Ratajczak M.Z.
Biological significance of the expression of HIV-related chemokine coreceptors (CCR5 and CXCR4) and their ligands by human hematopoietic cell lines.
Leukemia 14:1821-1832(2000)

PubMed=12592342; DOI=10.1038/sj.leu.2402799
Drexler H.G., Dirks W.G., Matsuo Y., MacLeod R.A.F.
False leukemia-lymphoma cell lines: an update on over 500 cell lines.
Leukemia 17:416-426(2003)

PubMed=20143388; DOI=10.1002/ijc.25242
Capes-Davis A., Theodosopoulos G., Atkin I., Drexler H.G., Kohara A., MacLeod R.A.F., Masters J.R.W., Nakamura Y., Reid Y.A., Reddel R.R., Freshney R.I.
Check your cultures! A list of cross-contaminated or misidentified cell lines.
Int. J. Cancer 127:1-8(2010)

Cell line collections (Providers) ATCC; CRL-9792 - Discontinued
KCB; KCB 200782YJ
Cell line databases/resources cancercelllines; CVCL_4360
Lonza; 1426
Anatomy/cell type resources BTO; BTO:0001550
Biological sample resources BioSample; SAMN03151657
Encyclopedic resources Wikidata; Q54828561
Polymorphism and mutation databases Cosmic; 1191696
Entry history
Entry creation04-Apr-2012
Last entry update02-May-2024
Version number30