ID   Dami
AC   CVCL_4360
SY   DAMI
DR   BTO; BTO_0001550
DR   ATCC; CRL-9792
DR   BioSample; SAMN03151657
DR   cancercelllines; CVCL_4360
DR   Cosmic; 1191696
DR   KCB; KCB 200782YJ
DR   Lonza; 1426
DR   Wikidata; Q54828561
RX   Patent=US5128245;
RX   PubMed=3196874;
RX   PubMed=9166871;
RX   PubMed=9326259;
RX   PubMed=9447816;
RX   PubMed=10508494;
RX   PubMed=11021758;
RX   PubMed=12592342;
RX   PubMed=20143388;
WW   Info; ATCC; -; https://www.atcc.org/en/support/technical-support/faqs/dami-atcc-crl-9792
WW   Info; ICLAC; -; https://iclac.org/wp-content/uploads/Cross-Contaminations_v13_distribution.xlsx
CC   Group: Patented cell line.
CC   Problematic cell line: Contaminated. Shown to be a HEL derivative (PubMed=9166871; PubMed=9326259; PubMed=9447816; PubMed=10508494; PubMed=12592342; PubMed=20143388). Originally thought to originate from the peripheral blood of a 57 year old male patient with megakaryoblastic leukemia.
CC   Registration: International Cell Line Authentication Committee, Register of Misidentified Cell Lines; ICLAC-00116.
CC   Registration: International Depositary Authority, American Type Culture Collection (ATCC); CRL-9792.
CC   Population: Caucasian.
CC   Doubling time: 24-30 hours (PubMed=3196874; Patent=US5128245).
CC   Sequence variation: Mutation; HGNC; HGNC:6192; JAK2; Simple; p.Val617Phe (c.1849G>T); ClinVar=VCV000014662; Zygosity=Homozygous (from parent cell line).
CC   Sequence variation: Mutation; HGNC; HGNC:11998; TP53; Simple; p.Met133Lys (c.398T>A); ClinVar=VCV002430159; Zygosity=Homozygous (from parent cell line).
CC   Discontinued: ATCC; CRL-9792; true.
CC   Derived from site: In situ; Peripheral blood; UBERON=UBERON_0000178.
CC   Cell type: Erythroblast; CL=CL_0000765.
ST   Source(s): ATCC=CRL-9792; CCRID
ST   Amelogenin: X (CCRID)
ST   Amelogenin: X,Y (ATCC=CRL-9792)
ST   CSF1PO: 10
ST   D13S317: 9,11
ST   D16S539: 11
ST   D18S51: 12,16
ST   D19S433: 11,13
ST   D21S11: 29,31.2
ST   D2S1338: 18,19
ST   D3S1358: 15
ST   D5S818: 11
ST   D7S820: 7
ST   D8S1179: 13,15
ST   FGA: 22,23
ST   TH01: 7
ST   TPOX: 11
ST   vWA: 14,17
DI   NCIt; C7152; Erythroleukemia
DI   ORDO; Orphanet_318; Acute erythroid leukemia
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
HI   CVCL_0001 ! HEL
SX   Male
AG   30Y
CA   Cancer cell line
DT   Created: 04-04-12; Last updated: 27-11-25; Version: 34
//
RX   PubMed=3196874; DOI=10.1182/blood.V72.6.1968.1968;
RA   Greenberg, Sheryl M.
RA   Rosenthal, David S.
RA   Greeley, Tammy A.
RA   Tantravahi, Ramana
RA   Handin, Robert I.
RT   "Characterization of a new megakaryocytic cell line: the Dami cell.";
RL   Blood 72:1968-1977(1988).
//
RX   PubMed=10508494; DOI=10.1002/(SICI)1097-0215(19991112)83:4<555::AID-IJC19>3.0.CO;2-2;
RA   MacLeod, Roderick A.F.
RA   Dirks, Wilhelm Gerhard
RA   Matsuo, Yoshinobu
RA   Kaufmann, Maren
RA   Milch, Herbert
RA   Drexler, Hans Gunther
RT   "Widespread intraspecies cross-contamination of human tumor cell lines
RT   arising at source.";
RL   Int. J. Cancer 83:555-563(1999).
//
RX   PubMed=11021758; DOI=10.1038/sj.leu.2401891;
RA   Majka, Marcin
RA   Rozmyslowicz, Tomasz
RA   Honczarenko, Marek J.
RA   Ratajczak, Janina
RA   Wasik, Mariusz A.
RA   Gaulton, Glen N.
RA   Ratajczak, Mariusz Zdzislaw
RT   "Biological significance of the expression of HIV-related chemokine
RT   coreceptors (CCR5 and CXCR4) and their ligands by human hematopoietic
RT   cell lines.";
RL   Leukemia 14:1821-1832(2000).
//
RX   PubMed=9166871; DOI=10.1182/blood.V89.11.4238;
RA   Handin, Robert I.
RT   "DAMI cell line.";
RL   Blood 89:4238-4238(1997).
//
RX   PubMed=20143388; DOI=10.1002/ijc.25242;
RA   Capes-Davis, Amanda
RA   Theodosopoulos, George
RA   Atkin, Isobel
RA   Drexler, Hans Gunther
RA   Kohara, Arihiro
RA   MacLeod, Roderick A.F.
RA   Masters, John R.W.
RA   Nakamura, Yukio
RA   Reid, Yvonne A.
RA   Reddel, Roger Robert
RA   Freshney, Robert Ian
RT   "Check your cultures! A list of cross-contaminated or misidentified
RT   cell lines.";
RL   Int. J. Cancer 127:1-8(2010).
//
RX   PubMed=12592342; DOI=10.1038/sj.leu.2402799;
RA   Drexler, Hans Gunther
RA   Dirks, Wilhelm Gerhard
RA   Matsuo, Yoshinobu
RA   MacLeod, Roderick A.F.
RT   "False leukemia-lymphoma cell lines: an update on over 500 cell
RT   lines.";
RL   Leukemia 17:416-426(2003).
//
RX   PubMed=9326259; DOI=10.1182/blood.V90.7.2850;
RA   MacLeod, Roderick A.F.
RA   Dirks, Wilhelm Gerhard
RA   Drexler, Hans Gunther
RT   "Early contamination of the Dami cell line by HEL.";
RL   Blood 90:2850-2851(1997).
//
RX   PubMed=9447816; DOI=10.1038/sj.leu.2400868;
RA   MacLeod, Roderick A.F.
RA   Dirks, Wilhelm Gerhard
RA   Reid, Yvonne A.
RA   Hay, Robert J.
RA   Drexler, Hans Gunther
RT   "Identity of original and late passage Dami megakaryocytes with HEL
RT   erythroleukemia cells shown by combined cytogenetics and DNA
RT   fingerprinting.";
RL   Leukemia 11:2032-2038(1997).
//
RX   Patent=US5128245;
RA   Greenberg, Sheryl M.
RA   Handin, Robert I.
RT   "Establishment, characterization and differentiation of a new
RT   megakaryocytic cell line, the Dami cells.";
RL   Patent number US5128245, 07-Jul-1992.
//