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Cellosaurus HBL-6 (CVCL_4221)

[Text version]
Cell line name HBL-6
Synonyms HBL6; BHL-6
Accession CVCL_4221
Resource Identification Initiative To cite this cell line use: HBL-6 (RRID:CVCL_4221)
Comments Registration: International Depositary Authority, American Type Culture Collection (ATCC); CRL-11762.
Population: Caucasian.
Transformant: NCBI_TaxID; 10376; Epstein-Barr virus (EBV).
Transformant: NCBI_TaxID; 37296; Human herpesvirus 8 (HHV-8/KSHV).
Derived from site: In situ; Ascites; UBERON=UBERON_0007795.
Cell type: B-cell; CL=CL_0000236.
Disease Primary effusion lymphoma (NCIt: C6915)
Primary effusion lymphoma (ORDO: Orphanet_48686)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Originate from same individual CVCL_1079 ! BC-1
Sex of cell Male
Age at sampling 46Y
Category Cancer cell line
Web pages Info; COPE; -; http://www.cells-talk.com/index.php/page/copelibrary?key=HBL-6
Publications

PubMed=8523568; DOI=10.1128/JVI.70.1.549-558.1996; PMCID=PMC189843
Patrick S. Moore, Shou-Jiang Gao, Geraldina Dominguez, Ethel Cesarman, Octavian Lungu, Daniel M. Knowles, Richard Garber, Philip E. Pellett, Duncan James McGeoch, Yuan Chang;
Primary characterization of a herpesvirus agent associated with Kaposi's sarcomae.
J. Virol. 70:549-558(1996)

PubMed=8684008
Gianluca Gaidano, Katarina Cechova, Y. Chang, Patrick S. Moore, Daniel M. Knowles, Riccardo Dalla-Favera;
Establishment of AIDS-related lymphoma cell lines from lymphomatous effusions.
Leukemia 10:1237-1240(1996)

Patent=US5849564
Yuan Chang, Roy A. Bohenzky, James J. Russo, Isidore Samiel Edelman, Patrick S. Moore;
Polypeptides from Kaposi's sarcoma-associated herpesvirus, DNA encoding same and uses thereof.
Patent number US5849564, 15-Dec-1998

PubMed=9473233; DOI=10.1182/blood.V91.5.1671
Chris Boshoff, Shou-Jiang Gao, Lyn E. Healy, Steve Matthews, Alero Jean Thomas, Lionel Jean Andre Coignet, Roger Allen Warnke, James A. Strauchen, Estella Matutes, Onsi Wadie Kamel, Patrick S. Moore ...Show all 13 authors... , Robin Anthony Weiss, Yuan Chang; Show fewer authors
Establishing a KSHV+ cell line (BCP-1) from peripheral blood and characterizing its growth in Nod/SCID mice.
Blood 91:1671-1679(1998)

PubMed=9766492; DOI=10.1038/sj.leu.2401160
Hans Gunther Drexler, Cord C. Uphoff, Gianluca Gaidano, Antonino Carbone;
Lymphoma cell lines: in vitro models for the study of HHV-8+ primary effusion lymphomas (body cavity-based lymphomas).
Leukemia 12:1507-1517(1998)

Patent=US5861500
Yuan Chang, Roy A. Bohenzky, James J. Russo, Isidore Samiel Edelman, Patrick S. Moore;
Kaposi's sarcoma-associated herpesvirus (KSHV) interleukin 6 (IL-6) and uses thereof.
Patent number US5861500, 19-Jan-1999

DOI=10.1016/B978-0-12-221970-2.50457-5
Hans Gunther Drexler;
The leukemia-lymphoma cell line factsbook.
(In book) ISBN 9780122219702; pp.1-733; Academic Press; London; United Kingdom (2001)

PubMed=15028022; DOI=10.1111/j.1440-1827.2004.01612.x
Katsuhito Kamimura, Hiroshi Hojo, Masafumi Abe;
Characterization of expression of protein kinase C isozymes in human B-cell lymphoma: relationship between its expression and prognosis.
Pathol. Int. 54:224-230(2004)

Cross-references
Anatomy/cell type resources BTO; BTO_0002723
Encyclopedic resources Wikidata; Q54881439
Polymorphism and mutation databases Cosmic; 1515189
Entry history
Entry creation04-Apr-2012
Last entry update10-Apr-2025
Version number19