ID   HBL-6
AC   CVCL_4221
SY   HBL6; BHL-6
DR   BTO; BTO:0002723
DR   Cosmic; 1515189
DR   Wikidata; Q54881439
RX   DOI=10.1016/B978-0-12-221970-2.50457-5;
RX   Patent=US5849564;
RX   Patent=US5861500;
RX   PubMed=8523568;
RX   PubMed=8684008;
RX   PubMed=9473233;
RX   PubMed=9766492;
RX   PubMed=15028022;
WW   http://www.cells-talk.com/index.php/page/copelibrary?key=HBL-6
CC   Registration: International Depositary Authority, American Type Culture Collection (ATCC); CRL-11762.
CC   Population: Caucasian.
CC   Transformant: NCBI_TaxID; 10376; Epstein-Barr virus (EBV).
CC   Transformant: NCBI_TaxID; 37296; Human herpesvirus 8 (HHV-8/KSHV).
CC   Derived from site: In situ; Ascites; UBERON=UBERON_0007795.
CC   Cell type: B-cell; CL=CL_0000236.
DI   NCIt; C6915; Primary effusion lymphoma
DI   ORDO; Orphanet_48686; Primary effusion lymphoma
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
OI   CVCL_1079 ! BC-1
SX   Male
AG   46Y
CA   Cancer cell line
DT   Created: 04-04-12; Last updated: 30-01-24; Version: 17
//
RX   DOI=10.1016/B978-0-12-221970-2.50457-5;
RA   Drexler H.G.;
RT   "The leukemia-lymphoma cell line factsbook.";
RL   (In) ISBN 9780122219702; pp.1-733; Academic Press; London (2001).
//
RX   Patent=US5849564;
RA   Chang Y., Bohenzky R.A., Russo J.J., Edelman I.S., Moore P.S.;
RT   "Polypeptides from Kaposi's sarcoma-associated herpesvirus, DNA
RT   encoding same and uses thereof.";
RL   Patent number US5849564, 15-Dec-1998.
//
RX   Patent=US5861500;
RA   Chang Y., Bohenzky R.A., Russo J.J., Edelman I.S., Moore P.S.;
RT   "Kaposi's sarcoma-associated herpesvirus (KSHV) interleukin 6 (IL-6)
RT   and uses thereof.";
RL   Patent number US5861500, 19-Jan-1999.
//
RX   PubMed=8523568; DOI=10.1128/JVI.70.1.549-558.1996;
RA   Moore P.S., Gao S.-J., Dominguez G., Cesarman E., Lungu O.,
RA   Knowles D.M., Garber R., Pellett P.E., McGeoch D.J., Chang Y.;
RT   "Primary characterization of a herpesvirus agent associated with
RT   Kaposi's sarcomae.";
RL   J. Virol. 70:549-558(1996).
//
RX   PubMed=8684008;
RA   Gaidano G., Cechova K., Chang Y., Moore P.S., Knowles D.M.,
RA   Dalla-Favera R.;
RT   "Establishment of AIDS-related lymphoma cell lines from lymphomatous
RT   effusions.";
RL   Leukemia 10:1237-1240(1996).
//
RX   PubMed=9473233; DOI=10.1182/blood.V91.5.1671;
RA   Boshoff C., Gao S.-J., Healy L.E., Matthews S., Thomas A.J.,
RA   Coignet L.J.A., Warnke R.A., Strauchen J.A., Matutes E., Kamel O.W.,
RA   Moore P.S., Weiss R.A., Chang Y.;
RT   "Establishing a KSHV+ cell line (BCP-1) from peripheral blood and
RT   characterizing its growth in Nod/SCID mice.";
RL   Blood 91:1671-1679(1998).
//
RX   PubMed=9766492; DOI=10.1038/sj.leu.2401160;
RA   Drexler H.G., Uphoff C.C., Gaidano G., Carbone A.;
RT   "Lymphoma cell lines: in vitro models for the study of HHV-8+ primary
RT   effusion lymphomas (body cavity-based lymphomas).";
RL   Leukemia 12:1507-1517(1998).
//
RX   PubMed=15028022; DOI=10.1111/j.1440-1827.2004.01612.x;
RA   Kamimura K., Hojo H., Abe M.;
RT   "Characterization of expression of protein kinase C isozymes in human
RT   B-cell lymphoma: relationship between its expression and prognosis.";
RL   Pathol. Int. 54:224-230(2004).
//