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Cellosaurus HBL-5 (CVCL_4219)

[Text version]
Cell line name HBL-5
Accession CVCL_4219
Resource Identification Initiative To cite this cell line use: HBL-5 (RRID:CVCL_4219)
Comments Population: Japanese.
Doubling time: 24 hours (PubMed=2486609); ~48 hours (PubMed=1309680).
Karyotypic information: Near tetraploid karyotype.
Transformant: NCBI_TaxID; 10376; Epstein-Barr virus (EBV).
Omics: Transcriptomics; Microarray.
Derived from site: In situ; Pleural effusion; UBERON=UBERON_0000175.
Cell type: B-cell; CL=CL_0000236.
Sequence variations
Disease EBV-related Burkitt lymphoma (NCIt: C27694)
Burkitt lymphoma (ORDO: Orphanet_543)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell Male
Age at sampling 4Y
Category Cancer cell line
Publications

PubMed=2486609
Masafumi Abe, Haruki Wakawa;
Establishment and characterization of human Burkitt's lymphoma cell (HBL-5).
Hum. Cell 2:195-196(1989)

PubMed=1309680; DOI=10.1002/1097-0142(19920201)69:3<763::AID-CNCR2820690325>3.0.CO;2-#
Masafumi Abe, Kazuhiro Tasaki, Kunihiko Tominaga, Shiro Fukuhara, Shosuke Imai, Toyoro Osato, Haruki Wakasa;
Characterization and comparison of two newly established Epstein-Barr virus (EBV)-negative and EBV-positive Burkitt's lymphoma cell lines EBV-negative cell line with a low level of expression of ICAM-1 molecule and EBV-positive cell line with a high level of expression of ICAM-1 molecule.
Cancer 69:763-771(1992)

PubMed=1592367; DOI=10.1002/hon.2900100205
Naoya Nakamura, Sayuri Suzuki, Nobutaka Ono, Kunihiko Tominaga, Hiroshi Hojo, Masafumi Abe, Haruki Wakasa;
A new monoclonal antibody which binds to the cytoplasm of large cell lymphomas.
Hematol. Oncol. 10:95-104(1992)

PubMed=9454894; DOI=10.3892/ijo.12.1.113
Takashi Akasaka, Hiroshi Akasaka, Hitoshi Ohno;
Polymerase chain reaction amplification of long DNA targets: application to analysis of chromosomal translocations in human B-cell tumors.
Int. J. Oncol. 12:113-121(1998)

PubMed=12967475; DOI=10.1111/j.1349-7006.2003.tb01518.x; PMCID=PMC11160262
Yoshitomo Maesako, Takashi Uchiyama, Hitoshi Ohno;
Comparison of gene expression profiles of lymphoma cell lines from transformed follicular lymphoma, Burkitt's lymphoma and de novo diffuse large B-cell lymphoma.
Cancer Sci. 94:774-781(2003)

PubMed=15028022; DOI=10.1111/j.1440-1827.2004.01612.x
Katsuhito Kamimura, Hiroshi Hojo, Masafumi Abe;
Characterization of expression of protein kinase C isozymes in human B-cell lymphoma: relationship between its expression and prognosis.
Pathol. Int. 54:224-230(2004)

PubMed=24504345; DOI=10.3892/ijo.2014.2291
Satoru Kobayashi, Tomohiko Taki, Hisao Nagoshi, Yoshiaki Chinen, Yuichi Yokokawa, Hirokazu Kanegane, Yosuke Matsumoto, Junya Kuroda, Shigeo Horiike, Kazuhiro Nishida, Masafumi Taniwaki;
Identification of novel fusion genes with 28S ribosomal DNA in hematologic malignancies.
Int. J. Oncol. 44:1193-1198(2014)

Cross-references
Anatomy/cell type resources BTO; BTO_0002527
Encyclopedic resources Wikidata; Q54881437
Entry history
Entry creation04-Apr-2012
Last entry update10-Apr-2025
Version number24