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Cellosaurus FM3Ats C1.T85 (CVCL_4201)

[Text version]

Cell line name FM3Ats C1.T85
Synonyms FM3A tscl.T85 Tsai; FM3A ts85; FM3Ats85; ts85; Ts85
Accession CVCL_4201
Resource Identification Initiative To cite this cell line use: FM3Ats C1.T85 (RRID:CVCL_4201)
Comments Characteristics: Has a thermolabile ubiquitin-like modifier-activating enzyme 1 (Uba1) (PubMed=6327059).
Doubling time: 18 hours (PubMed=6153988).
Transformant: ChEBI; CHEBI:21759; N-methyl-N'-nitro-N-nitrosoguanidine (MNNG).
Derived from sampling site: Mammary gland.
Disease Malignant neoplasms of the mouse mammary gland (NCIt: C21678)
Species of origin Mus musculus (Mouse) (NCBI Taxonomy: 10090)
Breed/subspecies: C3H/He.
Hierarchy Parent: CVCL_3869 (FM3A)
CVCL_A5JW (FM3A ts85R-MN3)
Sex of cell Female
Category Cancer cell line

PubMed=6153988; DOI=10.1016/0014-4827(80)90280-3
Mita S., Yasuda H., Marunouchi T., Ishiko S., Yamada M.
A temperature-sensitive mutant of cultured mouse cells defective in chromosome condensation.
Exp. Cell Res. 126:407-416(1980)

PubMed=7284331; DOI=10.1021/bi00518a028
Yasuda H., Matsumoto Y.-I., Mita S., Marunouchi T., Yamada M.-A.
A mouse temperature-sensitive mutant defective in H1 histone phosphorylation is defective in deoxyribonucleic acid synthesis and chromosome condensation.
Biochemistry 20:4414-4419(1981)

PubMed=6327059; DOI=10.1016/0092-8674(84)90299-x
Finley D., Ciechanover A., Varshavsky A.
Thermolability of ubiquitin-activating enzyme from the mammalian cell cycle mutant ts85.
Cell 37:43-55(1984)

PubMed=3049611; DOI=10.1016/S0021-9258(19)37648-3
Kulka R.G., Raboy B., Schuster R., Parag H.A., Diamond G., Ciechanover A., Marcus M.
A Chinese hamster cell cycle mutant arrested at G2 phase has a temperature-sensitive ubiquitin-activating enzyme, E1.
J. Biol. Chem. 263:15726-15731(1988)

PubMed=2156848; DOI=10.1016/S0021-9258(19)39329-9
Deveraux Q., Wells R., Rechsteiner M.
Ubiquitin metabolism in ts85 cells, a mouse carcinoma line that contains a thermolabile ubiquitin activating enzyme.
J. Biol. Chem. 265:6323-6329(1990)

Cell line collections ECACC; 87111904
RCB; RCB0033
Cell line databases/resources CLO; CLO_0003371
CLO; CLO_0050960
CLDB; cl1379
Encyclopedic resources Wikidata; Q54835040
Entry history
Entry creation04-Apr-2012
Last entry update20-May-2021
Version number9