ID   FM3Ats C1.T85
AC   CVCL_4201
SY   FM3A tscl.T85 Tsai; FM3A ts85; FM3Ats85; ts85; Ts85
DR   CLO; CLO_0003371
DR   CLO; CLO_0050960
DR   CLDB; cl1379
DR   ECACC; 87111904
DR   JCRB; JCRB0705
DR   RCB; RCB0033
DR   Wikidata; Q54835040
RX   PubMed=2156848;
RX   PubMed=3049611;
RX   PubMed=6153988;
RX   PubMed=6327059;
RX   PubMed=7284331;
CC   Characteristics: Has a thermolabile ubiquitin-like modifier-activating enzyme 1 (Uba1) (PubMed=6327059).
CC   Doubling time: 18 hours (PubMed=6153988).
CC   Transformant: ChEBI; CHEBI_21759; N-methyl-N'-nitro-N-nitrosoguanidine (MNNG).
CC   Derived from site: In situ; Mammary gland; UBERON=UBERON_0001911.
CC   Breed/subspecies: C3H/He.
DI   NCIt; C21678; Malignant neoplasms of the mouse mammary gland
OX   NCBI_TaxID=10090; ! Mus musculus (Mouse)
HI   CVCL_3869 ! FM3A
SX   Female
CA   Cancer cell line
DT   Created: 04-04-12; Last updated: 19-12-24; Version: 12
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RX   PubMed=2156848; DOI=10.1016/S0021-9258(19)39329-9;
RA   Deveraux Q., Wells R., Rechsteiner M.;
RT   "Ubiquitin metabolism in ts85 cells, a mouse carcinoma line that
RT   contains a thermolabile ubiquitin activating enzyme.";
RL   J. Biol. Chem. 265:6323-6329(1990).
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RX   PubMed=3049611; DOI=10.1016/S0021-9258(19)37648-3;
RA   Kulka R.G., Raboy B., Schuster R., Parag H.A., Diamond G.,
RA   Ciechanover A., Marcus M.;
RT   "A Chinese hamster cell cycle mutant arrested at G2 phase has a
RT   temperature-sensitive ubiquitin-activating enzyme, E1.";
RL   J. Biol. Chem. 263:15726-15731(1988).
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RX   PubMed=6153988; DOI=10.1016/0014-4827(80)90280-3;
RA   Mita S., Yasuda H., Marunouchi T., Ishiko S., Yamada M.-a.;
RT   "A temperature-sensitive mutant of cultured mouse cells defective in
RT   chromosome condensation.";
RL   Exp. Cell Res. 126:407-416(1980).
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RX   PubMed=6327059; DOI=10.1016/0092-8674(84)90299-x;
RA   Finley D.J., Ciechanover A., Varshavsky A.;
RT   "Thermolability of ubiquitin-activating enzyme from the mammalian cell
RT   cycle mutant ts85.";
RL   Cell 37:43-55(1984).
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RX   PubMed=7284331; DOI=10.1021/bi00518a028;
RA   Yasuda H., Matsumoto Y.-i., Mita S., Marunouchi T., Yamada M.-a.;
RT   "A mouse temperature-sensitive mutant defective in H1 histone
RT   phosphorylation is defective in deoxyribonucleic acid synthesis and
RT   chromosome condensation.";
RL   Biochemistry 20:4414-4419(1981).
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