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Cellosaurus CTAC (CVCL_4155)

[Text version]
Cell line name CTAC
Synonyms C_TAC
Accession CVCL_4155
Resource Identification Initiative To cite this cell line use: CTAC (RRID:CVCL_4155)
Comments Part of: FACC canine tumor cell line panel.
Doubling time: 15 hours (PubMed=27257868).
Omics: Deep exome analysis.
Omics: Transcriptome analysis by microarray.
Derived from site: In situ; Thyroid gland; UBERON=UBERON_0002046.
Sequence variations
  • Mutation; VGNC; 40436; ERBB2; Simple; p.Val659Glu (c.1976T>A); Zygosity=Homozygous (PubMed=31175136).
  • Mutation; VGNC; 47719; TP53; Simple; p.Thr114Met (c.341C>T); Zygosity=Homozygous (PubMed=31175136).
Disease Canine thyroid adenocarcinoma (NCIt: C132275)
Species of origin Canis lupus familiaris (Dog) (Canis familiaris) (NCBI Taxonomy: 9615)
Breed/subspecies: Boxer.
Sex of cell Female
Age at sampling 7Y
Category Cancer cell line
STR profile Source(s): PubMed=27197945; PubMed=31175136

Dog FHC2010227,231
Dog FHC2054151,164
Dog FHC2079275
Dog PEZ1119
Dog PEZ12263,277
Dog PEZ20176
Dog PEZ3113,119
Dog PEZ5103,115
Dog PEZ6179,183
Dog PEZ8228,240

Run an STR similarity search on this cell line

Kasza L.
Establishment and characterization of canine thyroid adenocarcinoma and canine melanoma cell lines.
Am. J. Vet. Res. 25:1178-1185(1964)

PubMed=29991117; DOI=10.1177/030098586700400405
Kasza L., Griesemer R.A.
The production of cytopathic changes in canine cell lines by infectious agents: cell lines derived from melanoma and thyroidal carcinoma.
Pathol. Vet. 4:378-390(1967)

PubMed=21908323; DOI=10.1177/1040638711408064
O'Donoghue L.E., Rivest J.P., Duval D.L.
Polymerase chain reaction-based species verification and microsatellite analysis for canine cell line validation.
J. Vet. Diagn. Invest. 23:780-785(2011)

PubMed=27257868; DOI=10.1371/journal.pone.0156689
Maeda J., Froning C.E., Brents C.A., Rose B.J., Thamm D.H., Kato T.A.
Intrinsic radiosensitivity and cellular characterization of 27 canine cancer cell lines.
PLoS ONE 11:E0156689-E0156689(2016)

PubMed=26842912; DOI=10.1111/vco.12197
Hartley G., Faulhaber E., Caldwell A., Coy J., Kurihara J., Guth A., Regan D., Dow S.
Immune regulation of canine tumour and macrophage PD-L1 expression.
Vet. Comp. Oncol. 15:534-549(2017)

PubMed=27197945; DOI=10.1111/vco.12192
Fowles J.S., Dailey D.D., Gustafson D.L., Thamm D.H., Duval D.L.
The Flint Animal Cancer Center (FACC) canine tumour cell line panel: a resource for veterinary drug discovery, comparative oncology and translational medicine.
Vet. Comp. Oncol. 15:481-492(2017)

PubMed=31175136; DOI=10.1158/1535-7163.MCT-18-1346
Das S., Idate R., Cronise K.E., Gustafson D.L., Duval D.L.
Identifying candidate druggable targets in canine cancer cell lines using whole exome sequencing.
Mol. Cancer Ther. 18:1460-1471(2019)

Cell line collections (Providers) ECACC; 90071812
Encyclopedic resources Wikidata; Q54814728
Gene expression databases GEO; GSM1974777
Entry history
Entry creation04-Apr-2012
Last entry update29-Jun-2023
Version number17