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Cellosaurus TOV-1946 (CVCL_4062)

[Text version]
Cell line name TOV-1946
Synonyms TOV1946
Accession CVCL_4062
Resource Identification Initiative To cite this cell line use: TOV-1946 (RRID:CVCL_4062)
Comments Doubling time: 1.3 +- 0.4 days (PubMed=18507860); 2.2 +- 0.26 days (PubMed=22931248).
Omics: Transcriptomics; Microarray.
Omics: Transcriptomics; RNAseq.
Miscellaneous: STR profile from personal communication of Mes-Masson, Anne-Marie.
Derived from site: In situ; Ovary; UBERON=UBERON_0000992.
Sequence variations
Disease High grade ovarian serous adenocarcinoma (NCIt: C105555)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Originate from same individual CVCL_4375 ! OV-1946
Sex of cell Female
Age at sampling 75Y
Category Cancer cell line
STR profile Source(s): Direct_author_submission

Markers:
AmelogeninX
CSF1PO9,10
D5S81811
D7S82011,12
D13S31712
D16S53911
D21S1130
TH019,9.3
TPOX8,10
vWA14,15

Run an STR similarity search on this cell line
Publications

PubMed=18507860; DOI=10.1186/1471-2407-8-152; PMCID=PMC2467432
Veronique Ouellet, Magdalena Zietarska, Lise Portelance, Julie Lafontaine, Jason Madore, Marie-Line Puiffe, Suzanna L. Arcand, Zhen Shen, Josee Hebert, Patricia N. Tonin, Diane Michele Provencher, Anne-Marie Mes-Masson;
Characterization of three new serous epithelial ovarian cancer cell lines.
BMC Cancer 8:152.1-152.18(2008)

PubMed=22585861; DOI=10.1158/2159-8290.CD-11-0224; PMCID=PMC5057396
Richard Marcotte, Kevin R. Brown, Fernando Jose Suarez Saiz, Azin Sayad, Konstantina Karamboulas, Paul M. Krzyzanowski, Fabrice Sircoulomb, Mauricio Medrano, Yaroslav Fedyshyn, Judice Lie-Yong Koh, Dewald van Dyk ...Show all 28 authors... , Bohdana Fedyshyn, Marianna Luhova, Glauber C. Brito, Franco J. Vizeacoumar, Frederick S. Vizeacoumar, Alessandro Datti, Dahlia Kasimer, Alla Buzina, Patricia Mero, Christine Misquitta, Josee Normand, Maliha Haider, Troy Ketela, Jeffrey L. Wrana, Robert Rottapel, Benjamin G. Neel, Jason Moffat; Show fewer authors
Essential gene profiles in breast, pancreatic, and ovarian cancer cells.
Cancer Discov. 2:172-189(2012)

PubMed=22931248; DOI=10.1186/1471-2407-12-379; PMCID=PMC3532154
Isabelle J. Letourneau, Michael C.J. Quinn, Lu-Lin Wang, Lise Portelance, Katia Y. Caceres, Louis Cyr, Nathalie Delvoye, Liliane Meunier, Manon de Ladurantaye, Zhen Shen, Suzanna L. Arcand ...Show all 14 authors... , Patricia N. Tonin, Diane Michele Provencher, Anne-Marie Mes-Masson; Show fewer authors
Derivation and characterization of matched cell lines from primary and recurrent serous ovarian cancer.
BMC Cancer 12:379.1-379.16(2012)

PubMed=28273451; DOI=10.1016/j.celrep.2017.02.028
Mauricio Medrano, Laudine Communal, Kevin R. Brown, Marcin Iwanicki, Josee Normand, Joshua Paterson, Fabrice Sircoulomb, Paul M. Krzyzanowski, Marian Novak, Sasha A. Doodnauth, Fernando Jose Suarez Saiz ...Show all 19 authors... , Jane Cullis, Rima Al-awar, Benjamin G. Neel, John McPherson, Ronny I. Drapkin, Laurie Ailles, Anne-Marie Mes-Masson, Robert Rottapel; Show fewer authors
Interrogation of functional cell-surface markers identifies CD151 dependency in high-grade serous ovarian cancer.
Cell Rep. 18:2343-2358(2017)

Cross-references
Cell line collections (Providers) CancerTools; 161770
Cell line databases/resources cancercelllines; CVCL_4062
Encyclopedic resources Wikidata; Q54972807
Gene expression databases GEO; GSM2475007
Polymorphism and mutation databases Cosmic; 1122314
Entry history
Entry creation04-Apr-2012
Last entry update10-Apr-2025
Version number21