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Cellosaurus TOV-1946 (CVCL_4062)

[Text version]
Cell line name TOV-1946
Synonyms TOV1946
Accession CVCL_4062
Resource Identification Initiative To cite this cell line use: TOV-1946 (RRID:CVCL_4062)
Comments Doubling time: 1.3 +- 0.4 days (PubMed=18507860); 2.2 +- 0.26 days (PubMed=22931248).
Omics: Transcriptome analysis by microarray.
Omics: Transcriptome analysis by RNAseq.
Miscellaneous: STR profile from personal communication of Mes-Masson A.-M.
Derived from site: In situ; Ovary; UBERON=UBERON_0000992.
Sequence variations
Disease High grade ovarian serous adenocarcinoma (NCIt: C105555)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Originate from same individual CVCL_4375 ! OV-1946
Sex of cell Female
Age at sampling 75Y
Category Cancer cell line
STR profile Source(s): Direct_author_submission

Markers:
AmelogeninX
CSF1PO9,10
D5S81811
D7S82011,12
D13S31712
D16S53911
D21S1130
TH019,9.3
TPOX8,10
vWA14,15

Run an STR similarity search on this cell line
Web pages http://dpsc.ccbr.utoronto.ca/cancer/get_cellline.pl?cellline=TOV-1946
Publications

PubMed=18507860; DOI=10.1186/1471-2407-8-152
Ouellet V., Zietarska M., Portelance L., Lafontaine J., Madore J., Puiffe M.-L., Arcand S.L., Shen Z., Hebert J., Tonin P.N., Provencher D.M., Mes-Masson A.-M.
Characterization of three new serous epithelial ovarian cancer cell lines.
BMC Cancer 8:152.1-152.18(2008)

PubMed=22585861; DOI=10.1158/2159-8290.CD-11-0224
Marcotte R., Brown K.R., Suarez Saiz F.J., Sayad A., Karamboulas K., Krzyzanowski P.M., Sircoulomb F., Medrano M., Fedyshyn Y., Koh J.L.Y., van Dyk D., Fedyshyn B., Luhova M., Brito G.C., Vizeacoumar F.J., Vizeacoumar F.S., Datti A., Kasimer D., Buzina A., Mero P., Misquitta C., Normand J., Haider M., Ketela T., Wrana J.L., Rottapel R., Neel B.G., Moffat J.
Essential gene profiles in breast, pancreatic, and ovarian cancer cells.
Cancer Discov. 2:172-189(2012)

PubMed=22931248; DOI=10.1186/1471-2407-12-379
Letourneau I.J., Quinn M.C.J., Wang L.-L., Portelance L., Caceres K.Y., Cyr L., Delvoye N., Meunier L., de Ladurantaye M., Shen Z., Arcand S.L., Tonin P.N., Provencher D.M., Mes-Masson A.-M.
Derivation and characterization of matched cell lines from primary and recurrent serous ovarian cancer.
BMC Cancer 12:379.1-379.16(2012)

PubMed=28273451; DOI=10.1016/j.celrep.2017.02.028
Medrano M., Communal L., Brown K.R., Iwanicki M., Normand J., Paterson J., Sircoulomb F., Krzyzanowski P.M., Novak M., Doodnauth S.A., Suarez Saiz F.J., Cullis J., Al-awar R., Neel B.G., McPherson J., Drapkin R.I., Ailles L., Mes-Masson A.-M., Rottapel R.
Interrogation of functional cell-surface markers identifies CD151 dependency in high-grade serous ovarian cancer.
Cell Rep. 18:2343-2358(2017)

Cross-references
Cell line databases/resources cancercelllines; CVCL_4062
Encyclopedic resources Wikidata; Q54972807
Gene expression databases GEO; GSM2475007
Polymorphism and mutation databases Cosmic; 1122314
Entry history
Entry creation04-Apr-2012
Last entry update05-Oct-2023
Version number18