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Cellosaurus Nb2-11 (CVCL_3860)

[Text version]
Cell line name Nb2-11
Synonyms Nb2-11C
Accession CVCL_3860
Resource Identification Initiative To cite this cell line use: Nb2-11 (RRID:CVCL_3860)
Comments Characteristics: Prolactin-dependent; metastatic (PubMed=9639394).
Doubling time: 12 hours (ECACC=97041101).
Disease Rat malignant lymphoma (NCIt: C60448)
Species of origin Rattus norvegicus (Rat) (NCBI Taxonomy: 10116)
Breed/subspecies: Nb.
Hierarchy Parent: CVCL_G705 (Nb2)
Sex of cell Male
Category Cancer cell line
Web pages Info; ECACC; -; https://www.culturecollections.org.uk/products/cell-cultures/ecacc-cell-line-profiles/nb2-11/
Publications

PubMed=1718958; DOI=10.1016/S0021-9258(18)54897-3
Suhad Ali, Isabelle Pellegrini, Paul A. Kelly;
A prolactin-dependent immune cell line (Nb2) expresses a mutant form of prolactin receptor.
J. Biol. Chem. 266:20110-20117(1991)

PubMed=8188682; DOI=10.1016/S0021-9258(17)36749-2
Jean-Jacques Lebrun, Suhad Ali, Luc Sofer, Axel Ullrich, Paul A. Kelly;
Prolactin-induced proliferation of Nb2 cells involves tyrosine phosphorylation of the prolactin receptor and its associated tyrosine kinase JAK2.
J. Biol. Chem. 269:14021-14026(1994)

PubMed=7895694; DOI=10.1210/endo.136.4.7895694
Cyril Blake Gilks, Susan D. Porter, Christopher Barker, Philip N. Tsichlis, Peter Wilhelm Gout;
Prolactin (PRL)-dependent expression of a zinc finger protein-encoding gene, Gfi-1, in Nb2 lymphoma cells: constitutive expression in autonomous sublines.
Endocrinology 136:1805-1808(1995)

PubMed=9639394; DOI=10.1002/(SICI)1097-0215(19980703)77:1<55::AID-IJC10>3.0.CO;2-8
Timothy E. Meyer, Hanqian Q. Liang, Arthur R. Buckley, Donna J. Buckley, Peter Wilhelm Gout, Edie H. Green, Ann M. Bode;
Changes in glutathione redox cycling and oxidative stress response in the malignant progression of NB2 lymphoma cells.
Int. J. Cancer 77:55-63(1998)

PubMed=9890649; DOI=10.1016/S0891-5849(98)00183-X
Ann M. Bode, Han-Qian Q. Liang, Edie H. Green, Timothy E. Meyer, Donna J. Buckley, Anne Norris, Peter Wilhelm Gout, Arthur R. Buckley;
Ascorbic acid recycling in Nb2 lymphoma cells: implications for tumor progression.
Free Radic. Biol. Med. 26:136-147(1999)

Cross-references
Cell line collections (Providers) ECACC; 97041101
NCBI_Iran; C606
Cell line databases/resources CLO; CLO_0007945
CLDB; cl5086
Encyclopedic resources Wikidata; Q54907521
Entry history
Entry creation04-Apr-2012
Last entry update10-Apr-2025
Version number10