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Cellosaurus Nb2-11 (CVCL_3860)

[Text version]
Cell line name Nb2-11
Synonyms Nb2-11C
Accession CVCL_3860
Resource Identification Initiative To cite this cell line use: Nb2-11 (RRID:CVCL_3860)
Comments Characteristics: Prolactin-dependent; metastatic (PubMed=9639394).
Doubling time: 12 hours (ECACC=97041101).
Disease Rat malignant lymphoma (NCIt: C60448)
Species of origin Rattus norvegicus (Rat) (NCBI Taxonomy: 10116)
Breed/subspecies: Nb.
Hierarchy Parent: CVCL_G705 (Nb2)
Sex of cell Male
Category Cancer cell line
Web pages Info; ECACC; -; https://www.culturecollections.org.uk/products/cell-cultures/ecacc-cell-line-profiles/nb2-11/
Publications

PubMed=1718958; DOI=10.1016/S0021-9258(18)54897-3
Ali S., Pellegrini I., Kelly P.A.
A prolactin-dependent immune cell line (Nb2) expresses a mutant form of prolactin receptor.
J. Biol. Chem. 266:20110-20117(1991)

PubMed=8188682; DOI=10.1016/S0021-9258(17)36749-2
Lebrun J.-J., Ali S., Sofer L., Ullrich A., Kelly P.A.
Prolactin-induced proliferation of Nb2 cells involves tyrosine phosphorylation of the prolactin receptor and its associated tyrosine kinase JAK2.
J. Biol. Chem. 269:14021-14026(1994)

PubMed=7895694; DOI=10.1210/endo.136.4.7895694
Gilks C.B., Porter S.D., Barker C., Tsichlis P.N., Gout P.W.
Prolactin (PRL)-dependent expression of a zinc finger protein-encoding gene, Gfi-1, in Nb2 lymphoma cells: constitutive expression in autonomous sublines.
Endocrinology 136:1805-1808(1995)

PubMed=9639394; DOI=10.1002/(sici)1097-0215(19980703)77:1<55::aid-ijc10>3.0.co;2-8
Meyer T.E., Liang H.Q., Buckley A.R., Buckley D.J., Gout P.W., Green E.H., Bode A.M.
Changes in glutathione redox cycling and oxidative stress response in the malignant progression of NB2 lymphoma cells.
Int. J. Cancer 77:55-63(1998)

PubMed=9890649; DOI=10.1016/S0891-5849(98)00183-X
Bode A.M., Liang H.-Q.Q., Green E.H., Meyer T.E., Buckley D.J., Norris A., Gout P.W., Buckley A.R.
Ascorbic acid recycling in Nb2 lymphoma cells: implications for tumor progression.
Free Radic. Biol. Med. 26:136-147(1999)

Cross-references
Cell line collections (Providers) ECACC; 97041101
NCBI_Iran; C606
Cell line databases/resources CLO; CLO_0007945
CLDB; cl5086
Encyclopedic resources Wikidata; Q54907521
Entry history
Entry creation04-Apr-2012
Last entry update10-Apr-2025
Version number10