ID   Nb2-11
AC   CVCL_3860
SY   Nb2-11C
DR   CLO; CLO_0007945
DR   CLDB; cl5086
DR   ECACC; 97041101
DR   NCBI_Iran; C606
DR   Wikidata; Q54907521
RX   PubMed=1718958;
RX   PubMed=7895694;
RX   PubMed=8188682;
RX   PubMed=9639394;
RX   PubMed=9890649;
WW   Info; ECACC; -; https://www.culturecollections.org.uk/products/cell-cultures/ecacc-cell-line-profiles/nb2-11/
CC   Characteristics: Prolactin-dependent; metastatic (PubMed=9639394).
CC   Doubling time: 12 hours (ECACC=97041101).
CC   Breed/subspecies: Nb.
DI   NCIt; C60448; Rat malignant lymphoma
OX   NCBI_TaxID=10116; ! Rattus norvegicus (Rat)
HI   CVCL_G705 ! Nb2
SX   Male
CA   Cancer cell line
DT   Created: 04-04-12; Last updated: 10-04-25; Version: 10
//
RX   PubMed=1718958; DOI=10.1016/S0021-9258(18)54897-3;
RA   Ali S., Pellegrini I., Kelly P.A.;
RT   "A prolactin-dependent immune cell line (Nb2) expresses a mutant form
RT   of prolactin receptor.";
RL   J. Biol. Chem. 266:20110-20117(1991).
//
RX   PubMed=7895694; DOI=10.1210/endo.136.4.7895694;
RA   Gilks C.B., Porter S.D., Barker C., Tsichlis P.N., Gout P.W.;
RT   "Prolactin (PRL)-dependent expression of a zinc finger
RT   protein-encoding gene, Gfi-1, in Nb2 lymphoma cells: constitutive
RT   expression in autonomous sublines.";
RL   Endocrinology 136:1805-1808(1995).
//
RX   PubMed=8188682; DOI=10.1016/S0021-9258(17)36749-2;
RA   Lebrun J.-J., Ali S., Sofer L., Ullrich A., Kelly P.A.;
RT   "Prolactin-induced proliferation of Nb2 cells involves tyrosine
RT   phosphorylation of the prolactin receptor and its associated tyrosine
RT   kinase JAK2.";
RL   J. Biol. Chem. 269:14021-14026(1994).
//
RX   PubMed=9639394; DOI=10.1002/(sici)1097-0215(19980703)77:1<55::aid-ijc10>3.0.co;2-8;
RA   Meyer T.E., Liang H.Q., Buckley A.R., Buckley D.J., Gout P.W., Green E.H.,
RA   Bode A.M.;
RT   "Changes in glutathione redox cycling and oxidative stress response in
RT   the malignant progression of NB2 lymphoma cells.";
RL   Int. J. Cancer 77:55-63(1998).
//
RX   PubMed=9890649; DOI=10.1016/S0891-5849(98)00183-X;
RA   Bode A.M., Liang H.-Q.Q., Green E.H., Meyer T.E., Buckley D.J.,
RA   Norris A., Gout P.W., Buckley A.R.;
RT   "Ascorbic acid recycling in Nb2 lymphoma cells: implications for tumor
RT   progression.";
RL   Free Radic. Biol. Med. 26:136-147(1999).
//