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Cellosaurus MH-22a (CVCL_3854)

[Text version]
Cell line name MH-22a
Synonyms MH-22A; MH 22A; MH 22a; MH22a; MG XXIIa; Mouse hepatoma 22a
Accession CVCL_3854
Resource Identification Initiative To cite this cell line use: MH-22a (RRID:CVCL_3854)
Comments Characteristics: Highly tumorigenic (PubMed=6274791).
Karyotypic information: Hypotriploid karyotype (DOI=10.37421/2684-4567.2021.5.121).
Transformant: ChEBI; CHEBI_82285; Ortho-aminoazotoluene (OAAT).
Omics: Variations; Array-based CGH.
Derived from site: In situ; Liver; UBERON=UBERON_0002107.
Disease Hepatocellular carcinoma of the mouse (NCIt: C38756)
Species of origin Mus musculus (Mouse) (NCBI Taxonomy: 10090)
Breed/subspecies: C3HA.
Hierarchy Children:
CVCL_E7C5 (MH-22a clone 22/4)CVCL_E7C6 (MH-22a clone 22/5)CVCL_E7C7 (MH-22a clone 22/6)
CVCL_E7C8 (MH-22a clone 22/8)CVCL_E7C9 (MH-22a clone 513)CVCL_E7CA (MH-22a clone 525)
CVCL_E7CB (MH-22a clone 544)
Originate from same individual CVCL_H613 ! H22
CVCL_E7BW ! H22-F25/L
Category Cancer cell line
STR profile Source(s): DOI=10.1134/S1990519X24700214

Markers:
Mouse STR 1-116,17
Mouse STR 1-217,18
Mouse STR 2-116
Mouse STR 3-214
Mouse STR 4-221.3
Mouse STR 5-514
Mouse STR 6-418,19
Mouse STR 6-715,16
Mouse STR 7-126.2
Mouse STR 8-116,17
Mouse STR 11-218
Mouse STR 12-117
Mouse STR 13-117.2
Mouse STR 15-322.3
Mouse STR 17-215,16
Mouse STR 18-318
Mouse STR 19-212
Mouse STR X-126,27

Run an STR similarity search on this cell line
Publications

DOI=10.1007/BF00803099
Aleksanyan Y.T., Basmadzhian M.E., Movsesian K.S., Manukyan L.A., Gevorkian S.K.
A line of transplantable cells obtained from a transplantable mouse hepatoma.
Bull. Exp. Biol. Med. 73:575-577(1972)

PubMed=6274791; PMCID=PMC1555000
Lavrovsky V.A., Viksler V.K.
Enhanced immune reactivity to hepatoma 22a cells in MTV-infected compared with MTV-free C3H mice.
Immunology 44:671-676(1981)

PubMed=9123902
Alexandrova S.A., Ermilov A.N., Kisliakova T.V., Artsybasheva I.V., Shvemberger I.N.
The use of B1-PCR method for studying the genomic polymorphism involved in malignant growth.
Vopr. Onkol. 42:48-52(1996)

PubMed=15995628
Alexandrova S.A., Shvemberger I.N.
Genetic variability of the mouse hepatoma cells MH-22a revealed by RAPD-PCR-fingerprinting under different conditions of cultivation.
Exp. Oncol. 27:114-119(2005)

DOI=10.37421/2684-4567.2021.5.121
Azawi S., Piaszinski K., Balachandran M., Liehr T., Rincic M.
Molecular cytogenomic characterization of two murine liver cancer cell lines: MH-22A and Hepa 1-6.
J. Genet. Genomes 5:1.1-1.6(2021)

DOI=10.1134/S1990519X24700214
Weiskirchen R., Kankel S., Liehr T.
Short tandem repeat profile for authentication of immortal murine cancer cell line MH-22A.
Cell Tissue Biol. 18:273-279(2024)

Cross-references
Cell line collections (Providers) ECACC; 96121721
Cell line databases/resources CLO; CLO_0007710
CLO; CLO_0007711
CLDB; cl3472
CLDB; cl5082
Encyclopedic resources Wikidata; Q54905507
Entry history
Entry creation04-Apr-2012
Last entry update10-Apr-2025
Version number9