| Cell line name |
MH-22a |
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| Synonyms |
MH-22A; MH 22A; MH 22a; MH22a; MG XXIIa; Mouse hepatoma 22a |
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| Accession |
CVCL_3854 |
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| Resource Identification Initiative |
To cite this cell line use: MH-22a (RRID:CVCL_3854) |
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| Comments |
Characteristics: Highly tumorigenic (PubMed=6274791).
Karyotypic information: Hypotriploid karyotype (DOI=10.37421/2684-4567.2021.5.121).
Transformant: ChEBI; CHEBI_82285; Ortho-aminoazotoluene (OAAT).
Omics: Variations; Array-based CGH.
Derived from site: In situ; Liver; UBERON=UBERON_0002107. |
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| Disease |
Hepatocellular carcinoma of the mouse (NCIt: C38756) |
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| Species of origin |
Mus musculus (Mouse)
(NCBI Taxonomy: 10090)
Breed/subspecies: C3HA. |
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| Hierarchy |
Children:
|
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| Originate from same individual |
CVCL_H613 ! H22
CVCL_E7BW ! H22-F25/L |
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| Category |
Cancer cell line |
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| STR profile |
Source(s): DOI=10.1134/S1990519X24700214
Markers:| Mouse STR 1-1 | 16,17 |
| Mouse STR 1-2 | 17,18 |
| Mouse STR 2-1 | 16 |
| Mouse STR 3-2 | 14 |
| Mouse STR 4-2 | 21.3 |
| Mouse STR 5-5 | 14 |
| Mouse STR 6-4 | 18,19 |
| Mouse STR 6-7 | 15,16 |
| Mouse STR 7-1 | 26.2 |
| Mouse STR 8-1 | 16,17 |
| Mouse STR 11-2 | 18 |
| Mouse STR 12-1 | 17 |
| Mouse STR 13-1 | 17.2 |
| Mouse STR 15-3 | 22.3 |
| Mouse STR 17-2 | 15,16 |
| Mouse STR 18-3 | 18 |
| Mouse STR 19-2 | 12 |
| Mouse STR X-1 | 26,27 |
Run an STR similarity search on this cell line |
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| Publications | DOI=10.1007/BF00803099
Yuri T. Aleksanyan, M.E. Basmadzhian, K.S. Movsesian, Larisa A. Manukyan, S.K. Gevorkian;
A line of transplantable cells obtained from a transplantable mouse hepatoma.
Bull. Exp. Biol. Med. 73:575-577(1972) PubMed=6274791; PMCID=PMC1555000
Vadim A. Lavrovsky, Victor K. Viksler;
Enhanced immune reactivity to hepatoma 22a cells in MTV-infected compared with MTV-free C3H mice.
Immunology 44:671-676(1981) PubMed=9123902
Svetlana Alekseevna Alexandrova, Alexandre N. Ermilov, Tatiana V. Kisliakova, I.V. Artsybasheva, Irina N. Shvemberger;
The use of B1-PCR method for studying the genomic polymorphism involved in malignant growth.
Vopr. Onkol. 42:48-52(1996) PubMed=15995628
Svetlana Alekseevna Alexandrova, Irina N. Shvemberger;
Genetic variability of the mouse hepatoma cells MH-22a revealed by RAPD-PCR-fingerprinting under different conditions of cultivation.
Exp. Oncol. 27:114-119(2005) DOI=10.37421/2684-4567.2021.5.121
Shaymaa Azawi, Katja Piaszinski, Milash Balachandran, Thomas Liehr, Martina Rincic;
Molecular cytogenomic characterization of two murine liver cancer cell lines: MH-22A and Hepa 1-6.
J. Genet. Genomes 5:1.1-1.6(2021) DOI=10.1134/S1990519X24700214
Ralf Weiskirchen, Stefanie Kankel, Thomas Liehr;
Short tandem repeat profile for authentication of immortal murine cancer cell line MH-22A.
Cell Tissue Biol. 18:273-279(2024) |
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| Cross-references |
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| Cell line collections (Providers) |
ECACC; 96121721
|
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| Cell line databases/resources |
CLO; CLO_0007710
CLO; CLO_0007711
CLDB; cl3472
CLDB; cl5082
|
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| Encyclopedic resources |
Wikidata; Q54905507
|
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| Entry history |
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| Entry creation | 04-Apr-2012 |
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| Last entry update | 10-Apr-2025 |
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| Version number | 9 |
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