ID   MH-22a
AC   CVCL_3854
SY   MH-22A; MH 22A; MH 22a; MH22a; MG XXIIa; Mouse hepatoma 22a
DR   CLO; CLO_0007710
DR   CLO; CLO_0007711
DR   CLDB; cl3472
DR   CLDB; cl5082
DR   ECACC; 96121721
DR   Wikidata; Q54905507
RX   DOI=10.1007/BF00803099;
RX   DOI=10.1134/S1990519X24700214;
RX   DOI=10.37421/2684-4567.2021.5.121;
RX   PubMed=6274791;
RX   PubMed=9123902;
RX   PubMed=15995628;
CC   Characteristics: Highly tumorigenic (PubMed=6274791).
CC   Karyotypic information: Hypotriploid karyotype (DOI=10.37421/2684-4567.2021.5.121).
CC   Transformant: ChEBI; CHEBI_82285; Ortho-aminoazotoluene (OAAT).
CC   Omics: Variations; Array-based CGH.
CC   Derived from site: In situ; Liver; UBERON=UBERON_0002107.
CC   Breed/subspecies: C3HA.
ST   Source(s): DOI=10.1134/S1990519X24700214
ST   Mouse STR 1-1: 16,17
ST   Mouse STR 1-2: 17,18
ST   Mouse STR 2-1: 16
ST   Mouse STR 3-2: 14
ST   Mouse STR 4-2: 21.3
ST   Mouse STR 5-5: 14
ST   Mouse STR 6-4: 18,19
ST   Mouse STR 6-7: 15,16
ST   Mouse STR 7-1: 26.2
ST   Mouse STR 8-1: 16,17
ST   Mouse STR 11-2: 18
ST   Mouse STR 12-1: 17
ST   Mouse STR 13-1: 17.2
ST   Mouse STR 15-3: 22.3
ST   Mouse STR 17-2: 15,16
ST   Mouse STR 18-3: 18
ST   Mouse STR 19-2: 12
ST   Mouse STR X-1: 26,27
DI   NCIt; C38756; Hepatocellular carcinoma of the mouse
OX   NCBI_TaxID=10090; ! Mus musculus (Mouse)
OI   CVCL_H613 ! H22
OI   CVCL_E7BW ! H22-F25/L
CA   Cancer cell line
DT   Created: 04-04-12; Last updated: 10-04-25; Version: 9
//
RX   DOI=10.1007/BF00803099;
RA   Aleksanyan Y.T., Basmadzhian M.E., Movsesian K.S., Manukyan L.A.,
RA   Gevorkian S.K.;
RT   "A line of transplantable cells obtained from a transplantable mouse
RT   hepatoma.";
RL   Bull. Exp. Biol. Med. 73:575-577(1972).
//
RX   DOI=10.1134/S1990519X24700214;
RA   Weiskirchen R., Kankel S., Liehr T.;
RT   "Short tandem repeat profile for authentication of immortal murine
RT   cancer cell line MH-22A.";
RL   Cell Tissue Biol. 18:273-279(2024).
//
RX   DOI=10.37421/2684-4567.2021.5.121;
RA   Azawi S., Piaszinski K., Balachandran M., Liehr T., Rincic M.;
RT   "Molecular cytogenomic characterization of two murine liver cancer
RT   cell lines: MH-22A and Hepa 1-6.";
RL   J. Genet. Genomes 5:1.1-1.6(2021).
//
RX   PubMed=6274791; PMCID=PMC1555000;
RA   Lavrovsky V.A., Viksler V.K.;
RT   "Enhanced immune reactivity to hepatoma 22a cells in MTV-infected
RT   compared with MTV-free C3H mice.";
RL   Immunology 44:671-676(1981).
//
RX   PubMed=9123902;
RA   Alexandrova S.A., Ermilov A.N., Kisliakova T.V., Artsybasheva I.V.,
RA   Shvemberger I.N.;
RT   "The use of B1-PCR method for studying the genomic polymorphism
RT   involved in malignant growth.";
RL   Vopr. Onkol. 42:48-52(1996).
//
RX   PubMed=15995628;
RA   Alexandrova S.A., Shvemberger I.N.;
RT   "Genetic variability of the mouse hepatoma cells MH-22a revealed by
RT   RAPD-PCR-fingerprinting under different conditions of cultivation.";
RL   Exp. Oncol. 27:114-119(2005).
//