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Cellosaurus MAT-LyLu (CVCL_3848)

[Text version]
Cell line name MAT-LyLu
Synonyms Mat-Ly-Lu; MATLyLu; R-3327 MAT-LyLu; R3327-MATLyLu; R3327-MatLyLu; Dunning R 3327 MAT LyLu; Metastatic AT tumor able to disseminate to lymph nodes and lung
Accession CVCL_3848
Secondary accession CVCL_2168
Resource Identification Initiative To cite this cell line use: MAT-LyLu (RRID:CVCL_3848)
Comments Doubling time: ~15 hours (DSMZ=ACC-609).
Derived from site: In situ; Prostate; UBERON=UBERON_0002367.
Disease Adenocarcinoma of the rat prostate (NCIt: C64013)
Species of origin Rattus norvegicus (Rat) (NCBI Taxonomy: 10116)
Breed/subspecies: Copenhagen; RS=RS_0000184.
Hierarchy Parent: CVCL_3568 (R-3327-AT-1)
Children:
CVCL_Y659 (MAT-LyLu-B-1)CVCL_3849 (MAT-LyLu-B-2)
Sex of cell Male
Age at sampling 1Y10M
Category Cancer cell line
Web pages Info; IdeaConnection; -; https://www.ideaconnection.com/patents/5871-R-3327-AT-1-Rat-Prostatic-Cancer-Cell-Line.html
Publications

PubMed=7251319
John T. Isaacs, George W. Yu, Donald Straley Coffey;
The characterization of a newly identified, highly metastatic variety of Dunning R 3327 rat prostatic adenocarcinoma system: the MAT LyLu tumor.
Invest. Urol. 19:20-23(1981)

PubMed=3774632; DOI=10.1002/pros.2990090306
John T. Isaacs, William B. Isaacs, Wouter F.J. Feitz, Jacques Scheres;
Establishment and characterization of seven Dunning rat prostatic cancer cell lines and their use in developing methods for predicting metastatic abilities of prostatic cancers.
Prostate 9:261-281(1986)

PubMed=3174494; DOI=10.1002/pros.2990130208
John T. Isaacs, Bharati Hukku;
Nonrandom involvement of chromosome 4 in the progression of rat prostatic cancer.
Prostate 13:165-188(1988)

PubMed=7910810; DOI=10.1002/ijc.2910570519
Imtiar Bashir, Karol Sikora, Paul Abel, Christopher S. Foster;
Establishment and in vivo characterization of multidrug-resistant Dunning R3327 rat prostate-carcinoma cell-lines.
Int. J. Cancer 57:719-726(1994)

PubMed=8687134
Prakash K. Pandalai, Mary Jo Pilat, Kosuki Yamazaki, Harmesh Naik, Kenneth James Pienta;
The effects of omega-3 and omega-6 fatty acids on in vitro prostate cancer growth.
Anticancer Res. 16:815-820(1996)

PubMed=23467722; DOI=10.3892/or.2013.2323
Ewa Musialik, Damian Ryszawy, Zbigniew Madeja, Wlodzimierz Korohoda;
Morpho-physiological heterogeneity of cells within two rat prostate carcinoma cell lines AT-2 and MAT-LyLu differing in the degree of malignancy observed by cell cloning and the effects of caffeine, theophylline and papaverine upon a proportion of the clones.
Oncol. Rep. 29:1789-1796(2013)

Cross-references
Cell line collections (Providers) ATCC; JHU-5 - Discontinued
ATCC; JHU-92 - Discontinued
CancerTools; 156410
DSMZ; ACC-609
ECACC; 94101454
Cell line databases/resources CLO; CLO_0007541
CLDB; cl3338
DSMZCellDive; ACC-609
Anatomy/cell type resources BTO; BTO_0003306
Chemistry resources ChEMBL-Cells; CHEMBL3307987
ChEMBL-Targets; CHEMBL612579
PubChem_Cell_line; CVCL_3848
Encyclopedic resources Wikidata; Q54904059
Entry history
Entry creation04-Apr-2012
Last entry update10-Apr-2025
Version number21