ID   MAT-LyLu
AC   CVCL_3848
AS   CVCL_2168
SY   Mat-Ly-Lu; MATLyLu; R-3327 MAT-LyLu; R3327-MATLyLu; R3327-MatLyLu; Dunning R 3327 MAT LyLu; Metastatic AT tumor able to disseminate to lymph nodes and lung
DR   BTO; BTO_0003306
DR   CLO; CLO_0007541
DR   CLDB; cl3338
DR   ATCC; JHU-5
DR   ATCC; JHU-92
DR   CancerTools; 156410
DR   ChEMBL-Cells; CHEMBL3307987
DR   ChEMBL-Targets; CHEMBL612579
DR   DSMZ; ACC-609
DR   DSMZCellDive; ACC-609
DR   ECACC; 94101454
DR   PubChem_Cell_line; CVCL_3848
DR   Wikidata; Q54904059
RX   PubMed=3174494;
RX   PubMed=3774632;
RX   PubMed=7251319;
RX   PubMed=7910810;
RX   PubMed=8687134;
RX   PubMed=23467722;
WW   Info; IdeaConnection; -; https://www.ideaconnection.com/patents/5871-R-3327-AT-1-Rat-Prostatic-Cancer-Cell-Line.html
CC   Doubling time: ~15 hours (DSMZ=ACC-609).
CC   Discontinued: ATCC; JHU-5; true.
CC   Discontinued: ATCC; JHU-92; true.
CC   Derived from site: In situ; Prostate; UBERON=UBERON_0002367.
CC   Breed/subspecies: Copenhagen; RS=RS_0000184.
DI   NCIt; C64013; Adenocarcinoma of the rat prostate
OX   NCBI_TaxID=10116; ! Rattus norvegicus (Rat)
HI   CVCL_3568 ! R-3327-AT-1
SX   Male
AG   1Y10M
CA   Cancer cell line
DT   Created: 04-04-12; Last updated: 10-04-25; Version: 21
CH   CVCL_Y659 ! MAT-LyLu-B-1
CH   CVCL_3849 ! MAT-LyLu-B-2
//
RX   PubMed=7910810; DOI=10.1002/ijc.2910570519;
RA   Bashir, Imtiar
RA   Sikora, Karol
RA   Abel, Paul
RA   Foster, Christopher S.
RT   "Establishment and in vivo characterization of multidrug-resistant
RT   Dunning R3327 rat prostate-carcinoma cell-lines.";
RL   Int. J. Cancer 57:719-726(1994).
//
RX   PubMed=3174494; DOI=10.1002/pros.2990130208;
RA   Isaacs, John T.
RA   Hukku, Bharati
RT   "Nonrandom involvement of chromosome 4 in the progression of rat
RT   prostatic cancer.";
RL   Prostate 13:165-188(1988).
//
RX   PubMed=8687134;
RA   Pandalai, Prakash K.
RA   Pilat, Mary Jo
RA   Yamazaki, Kosuki
RA   Naik, Harmesh
RA   Pienta, Kenneth James
RT   "The effects of omega-3 and omega-6 fatty acids on in vitro prostate
RT   cancer growth.";
RL   Anticancer Res. 16:815-820(1996).
//
RX   PubMed=3774632; DOI=10.1002/pros.2990090306;
RA   Isaacs, John T.
RA   Isaacs, William B.
RA   Feitz, Wouter F.J.
RA   Scheres, Jacques
RT   "Establishment and characterization of seven Dunning rat prostatic
RT   cancer cell lines and their use in developing methods for predicting
RT   metastatic abilities of prostatic cancers.";
RL   Prostate 9:261-281(1986).
//
RX   PubMed=23467722; DOI=10.3892/or.2013.2323;
RA   Musialik, Ewa
RA   Ryszawy, Damian
RA   Madeja, Zbigniew
RA   Korohoda, Wlodzimierz
RT   "Morpho-physiological heterogeneity of cells within two rat prostate
RT   carcinoma cell lines AT-2 and MAT-LyLu differing in the degree of
RT   malignancy observed by cell cloning and the effects of caffeine,
RT   theophylline and papaverine upon a proportion of the clones.";
RL   Oncol. Rep. 29:1789-1796(2013).
//
RX   PubMed=7251319;
RA   Isaacs, John T.
RA   Yu, George W.
RA   Coffey, Donald Straley
RT   "The characterization of a newly identified, highly metastatic variety
RT   of Dunning R 3327 rat prostatic adenocarcinoma system: the MAT LyLu
RT   tumor.";
RL   Invest. Urol. 19:20-23(1981).
//