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Cellosaurus MA-104 (CVCL_3845)

[Text version]
Cell line name MA-104
Synonyms Ma-104; MA 104; MA104; Microbiological Associates-104
Accession CVCL_3845
Resource Identification Initiative To cite this cell line use: MA-104 (RRID:CVCL_3845)
Comments Group: Non-human primate cell line.
Problematic cell line: Misidentified. Originally thought to be of Rhesus macaque origin but found to be from African Green monkey (PubMed=4043530; PubMed=20143388) and more precisely from Chlorocebus pygerythrus (PubMed=34737324).
Registration: International Cell Line Authentication Committee, Register of Misidentified Cell Lines; ICLAC-00077.
Virology: Susceptible to infection by many viruses (arboviruses, reoviruses, rotaviruses, etc.).
Virology: Susceptible to infection by SARS coronavirus (SARS-CoV). Produces a lytic infection (PubMed=15731278; PubMed=16494729).
Virology: Susceptible to infection by SARS coronavirus 2 (SARS-CoV-2) (COVID-19) (PubMed=33389257).
Derived from site: In situ; Fetal kidney; UBERON=UBERON_0002113.
Species of origin Chlorocebus pygerythrus (Vervet monkey) (Cercopithecus pygerythrus) (NCBI Taxonomy: 60710)
Hierarchy Children:
CVCL_1K12 (9009B)CVCL_A0XU (CL2621)CVCL_3846 (MA-104 Clone 1)
CVCL_4540 (MARC-145)CVCL_3774 (PSP-36)
Sex of cell Sex unspecified
Age at sampling Fetus
Category Spontaneously immortalized cell line
Web pages https://www.atcc.org/en/support/technical-support/faqs/ma-104-atcc-crl-2378

PubMed=4626908; DOI=10.1128/am.24.1.62-69.1972
Myers M.G., Vincent M.M., Hensen S.A., Tauraso N.M.
Problems in the laboratory isolation of simian hemorrhagic fever viruses and isolation of the agent responsible for the Sussex-69 epizootic.
Appl. Microbiol. 24:62-69(1972)

Whitaker A.M., Hayward C.J.
The characterization of three monkey kidney cell lines.
Dev. Biol. Stand. 60:125-131(1985)

PubMed=15731278; DOI=10.1128/JVI.79.6.3846-3850.2005
Mossel E.C., Huang C., Narayanan K., Makino S., Tesh R.B., Peters C.J.
Exogenous ACE2 expression allows refractory cell lines to support severe acute respiratory syndrome coronavirus replication.
J. Virol. 79:3846-3850(2005)

PubMed=16494729; DOI=10.3201/eid1201.050496
Kaye M., Druce J., Tran T., Kostecki R., Chibo D., Morris J., Catton M., Birch C.
SARS-associated coronavirus replication in cell lines.
Emerg. Infect. Dis. 12:128-133(2006)

PubMed=19941903; DOI=10.1016/j.jviromet.2009.11.022
Karger A., Bettin B., Lenk M., Mettenleiter T.C.
Rapid characterisation of cell cultures by matrix-assisted laser desorption/ionisation mass spectrometric typing.
J. Virol. Methods 164:116-121(2010)

PubMed=20143388; DOI=10.1002/ijc.25242
Capes-Davis A., Theodosopoulos G., Atkin I., Drexler H.G., Kohara A., MacLeod R.A.F., Masters J.R.W., Nakamura Y., Reid Y.A., Reddel R.R., Freshney R.I.
Check your cultures! A list of cross-contaminated or misidentified cell lines.
Int. J. Cancer 127:1-8(2010)

PubMed=26235236; DOI=10.1016/j.jviromet.2015.07.016
Otto P.H., Reetz J., Eichhorn W., Herbst W., Elschner M.C.
Isolation and propagation of the animal rotaviruses in MA-104 cells -- 30 years of practical experience.
J. Virol. Methods 223:88-95(2015)

PubMed=28046048; DOI=10.1371/journal.pone.0169391
Dotti S., Lombardo T., Villa R., Cacciamali A., Zanotti C., Andreani N.A., Cinotti S., Ferrari M.
Transformation and tumorigenicity testing of simian cell lines and evaluation of poliovirus replication.
PLoS ONE 12:E0169391-E0169391(2017)

PubMed=33389257; DOI=10.1007/s10096-020-04106-0
Wurtz N., Penant G., Jardot P., Duclos N., La Scola B.
Culture of SARS-CoV-2 in a panel of laboratory cell lines, permissivity, and differences in growth profile.
Eur. J. Clin. Microbiol. Infect. Dis. 40:477-484(2021)

PubMed=34737324; DOI=10.1038/s41598-021-00779-5
Lung O., Candlish R.C., Nebroski M., Kruckiewicz P., Buchanan C., Moniwa M.
High-throughput sequencing for species authentication and contamination detection of 63 cell lines.
Sci. Rep. 11:21657-21657(2021)

Cell line collections (Providers) ATCC; CRL-2378 - Discontinued
BCRJ; 0157
CLS; 305007
ECACC; 85102918
KCB; KCB 2010001YJ
NCBI_Iran; C486
RCB; RCB0994
Cell line databases/resources CLO; CLO_0007492
CLO; CLO_0007494
CLO; CLO_0051423
CLDB; cl3324
CLDB; cl3325
CLDB; cl3326
CLDB; cl3327
Anatomy/cell type resources BTO; BTO:0004983
Biological sample resources BioSample; SAMN03152038
Encyclopedic resources Wikidata; Q54903682
Gene expression databases GEO; GSM758845
GEO; GSM758846
GEO; GSM758847
GEO; GSM758848
GEO; GSM758849
GEO; GSM758850
GEO; GSM758851
GEO; GSM758852
GEO; GSM758853
GEO; GSM758854
GEO; GSM758855
GEO; GSM758856
GEO; GSM758857
GEO; GSM758858
GEO; GSM758859
Entry history
Entry creation04-Apr-2012
Last entry update30-Jan-2024
Version number30