Cellosaurus cell line RPE-J (CVCL

Cellosaurus RPE-J (CVCL_3789)

Cross-references
Cell line name	RPE-J
Accession	CVCL_3789
Resource Identification Initiative	To cite this cell line use: RPE-J (RRID:CVCL_3789)
Comments	Characteristics: At the restrictive temperature (40 Celsius) this cell line acquires a differentiated polarized RPE phenotype (PubMed=8383696). Transformant: NCBI_TaxID; 1891767; Simian virus 40 (SV40) (Note=tsA). Omics: Proteomics; 2DE-MS. Derived from site: In situ; Eye, retina, retinal pigment epithelium; UBERON=UBERON_0001782. Cell type: Retinal pigment epithelial cell; CL=CL_0002586.
Species of origin	Rattus norvegicus (Rat) (NCBI Taxonomy: 10116) Breed/subspecies: Long-Evans; RS=RS_0000347.
Sex of cell	Sex unspecified
Age at sampling	7D
Category	Transformed cell line
Web pages	Info; LRI; -; https://web.archive.org/web/20100714222258/http://www.lerner.ccf.org/eye/crabb/research/gel_rpe-j_cell.php
Publications	PubMed=8383696; DOI=10.1242/jcs.104.1.37 Nabi I.R., Mathews A.P., Cohen-Gould L., Gundersen D., Rodriguez-Boulan E.J. Immortalization of polarized rat retinal pigment epithelium. J. Cell Sci. 104:37-49(1993) PubMed=11825020; DOI=10.1006/exer.2001.1058 West K.A., Yan L., Miyagi M., Crabb J.S., Marmorstein A.D., Marmorstein L.Y., Crabb J.W. Proteome survey of proliferating and differentiating rat RPE-J cells. Exp. Eye Res. 73:479-491(2001) PubMed=27050416; DOI=10.1371/journal.pone.0153011; PMCID=PMC4822873 Ferrario A., Luna M.C., Rucker N., Wong S., Lederman A., Kim J., Gomer C.J. Targeting survivin enhances chemosensitivity in retinoblastoma cells and orthotopic tumors. PLoS ONE 11:e0153011.1-e0153011.16(2016)
Cell line collections (Providers)	ATCC; CRL-2240
Cell line databases/resources	CLO; CLO_0008866
Encyclopedic resources	Wikidata; Q54951142
Entry history
Entry creation	04-Apr-2012
Last entry update	10-Apr-2025
Version number	16