ID   RPE-J
AC   CVCL_3789
DR   CLO; CLO_0008866
DR   ATCC; CRL-2240
DR   Wikidata; Q54951142
RX   PubMed=8383696;
RX   PubMed=11825020;
RX   PubMed=27050416;
WW   Info; LRI; -; https://web.archive.org/web/20100714222258/http://www.lerner.ccf.org/eye/crabb/research/gel_rpe-j_cell.php
CC   Characteristics: At the restrictive temperature (40 Celsius) this cell line acquires a differentiated polarized RPE phenotype (PubMed=8383696).
CC   Transformant: NCBI_TaxID; 1891767; Simian virus 40 (SV40) (Note=tsA).
CC   Omics: Proteomics; 2DE-MS.
CC   Derived from site: In situ; Eye, retina, retinal pigment epithelium; UBERON=UBERON_0001782.
CC   Cell type: Retinal pigment epithelial cell; CL=CL_0002586.
CC   Breed/subspecies: Long-Evans; RS=RS_0000347.
OX   NCBI_TaxID=10116; ! Rattus norvegicus (Rat)
SX   Sex unspecified
AG   7D
CA   Transformed cell line
DT   Created: 04-04-12; Last updated: 10-04-25; Version: 16
//
RX   PubMed=8383696; DOI=10.1242/jcs.104.1.37;
RA   Nabi I.R., Mathews A.P., Cohen-Gould L., Gundersen D.,
RA   Rodriguez-Boulan E.J.;
RT   "Immortalization of polarized rat retinal pigment epithelium.";
RL   J. Cell Sci. 104:37-49(1993).
//
RX   PubMed=11825020; DOI=10.1006/exer.2001.1058;
RA   West K.A., Yan L., Miyagi M., Crabb J.S., Marmorstein A.D.,
RA   Marmorstein L.Y., Crabb J.W.;
RT   "Proteome survey of proliferating and differentiating rat RPE-J cells.";
RL   Exp. Eye Res. 73:479-491(2001).
//
RX   PubMed=27050416; DOI=10.1371/journal.pone.0153011; PMCID=PMC4822873;
RA   Ferrario A., Luna M.C., Rucker N., Wong S., Lederman A., Kim J.,
RA   Gomer C.J.;
RT   "Targeting survivin enhances chemosensitivity in retinoblastoma cells
RT   and orthotopic tumors.";
RL   PLoS ONE 11:e0153011.1-e0153011.16(2016).
//