Cellosaurus cell line McCoy (CVCL

Cellosaurus McCoy (CVCL_3742)

Cross-references
Cell line name	McCoy
Synonyms	MCCOY; Mc Coy; McCoy B; McC
Accession	CVCL_3742
Resource Identification Initiative	To cite this cell line use: McCoy (RRID:CVCL_3742)
Comments	Problematic cell line: Misidentified. Originally thought to be of human origin but found to be a mouse NCTC clone 929 derivative (PubMed=6451928; PubMed=20143388). Were thought to originate from the synovial fluid in the knee joint of a patient suffering from degenerative arthritis. Registration: International Cell Line Authentication Committee, Register of Misidentified Cell Lines; ICLAC-00079. Virology: Not susceptible to infection by SARS coronavirus 2 (SARS-CoV-2) (COVID-19) (PubMed=33389257). Derived from site: In situ; Connective tissue; UBERON=UBERON_0002384. Cell type: Fibroblast; CL=CL_0000057.
Species of origin	Mus musculus (Mouse) (NCBI Taxonomy: 10090) Breed/subspecies: C3H/An.
Hierarchy	Parent: CVCL_0462 (NCTC clone 929)
Sex of cell	Male
Age at sampling	100D
Category	Spontaneously immortalized cell line
Web pages	Info; ICLAC; -; https://iclac.org/wp-content/uploads/Cross-Contaminations_v13_distribution.xlsx Provider; Vircell; -; https://www.vircell.com/en/products/mccoy-cell-line
Publications	PubMed=13531635; DOI=10.1007/BF00340146 Charles Marc Pomerat, Sidney P. Kent, Loren C. Logie; Irradiation of cells in tissue culture. I. Giant cell induction in strain cultures versus elements from primary explants. Z. Zellforsch. Mikrosk. Anat. 47:158-174(1957) PubMed=4110420; DOI=10.1128/am.23.1.123-129.1972; PMCID=PMC380289 Francis B. Gordon, Harry R. Dressler, Alice Lee Quan, William T. McQuilkin, John I. Thomas; Effect of ionizing irradiation on susceptibility of McCoy cell cultures to Chlamydia trachomatis. Appl. Microbiol. 23:123-129(1972) PubMed=6451928; DOI=10.1126/science.6451928 Walter Anthony Nelson-Rees, David W. Daniels, Robert R. Flandermeyer; Cross-contamination of cells in culture. Science 212:446-452(1981) PubMed=2754009; DOI=10.1128/jcm.27.6.1399-1400.1989; PMCID=PMC267569 Eliane A.P.M. Thewessen, Ingrid Freundt, J.H. van Rijsoort-Vos, Ernst Stolz, Marc F. Michel, Johan H.T. Wagenvoort; Comparison of HeLa 229 and McCoy cell cultures for detection of Chlamydia trachomatis in clinical specimens. J. Clin. Microbiol. 27:1399-1400(1989) PubMed=20143388; DOI=10.1002/ijc.25242 Amanda Capes-Davis, George Theodosopoulos, Isobel Atkin, Hans Gunther Drexler, Arihiro Kohara, Roderick A.F. MacLeod, John R.W. Masters, Yukio Nakamura, Yvonne A. Reid, Roger Robert Reddel, Robert Ian Freshney; Check your cultures! A list of cross-contaminated or misidentified cell lines. Int. J. Cancer 127:1-8(2010) PubMed=33389257; DOI=10.1007/s10096-020-04106-0; PMCID=PMC7778494 Nathalie Wurtz, Gwilherm Penant, Priscilla Jardot, Nathalie Duclos, Bernard La Scola; Culture of SARS-CoV-2 in a panel of laboratory cell lines, permissivity, and differences in growth profile. Eur. J. Clin. Microbiol. Infect. Dis. 40:477-484(2021)
Cell line collections (Providers)	ATCC; CRL-1696 BCRC; 60064 BCRJ; 0160 ECACC; 90010305 IZSLER; BS CL 62 NCBI_Iran; C123
Cell line databases/resources	CLO; CLO_0007573 CLO; CLO_0007598 CLDB; cl3349 CLDB; cl3350 CLDB; cl3352
Biological sample resources	BioSample; SAMN03151926
Encyclopedic resources	Wikidata; Q54904270
Entry history
Entry creation	04-Apr-2012
Last entry update	10-Apr-2025
Version number	26